Autophagy is an evolutionarily conserved, lysosome-dependent catabolic process whereby
cytoplasmic components, including damaged organelles, protein aggregates and lipid …

Autophagy is a lysosomal degradation pathway recycling intracellular long-lived proteins
and damaged organelles, thereby maintaining cellular homeostasis. In addition to …

Abstract Knowledge gained over the past 10 years about the mechanisms that underpin
autophagy has provided a universal framework for studies of diverse physiological and …

Autophagy functions to degrade and recycle intracellular proteins and damaged organelles,
maintaining the normal cellular function. Autophagy has been shown to play an important …

Obesity poses a severe threat to human health, including the increased prevalence of
hypertension, insulin resistance, diabetes mellitus, cancer, inflammation, sleep apnoea and …

Autophagy is a critical quality control pathway that is conserved across diverse systems
ranging from simple unicellular organisms like yeast to more complex systems, for instance …

Autophagy is a cellular pathway crucial for development, differentiation, survival and
homeostasis. Autophagy can provide protection against aging and a number of pathologies …

Diabetes mellitus (DM) is an endocrine disorder. In coming decades it will be one of the
leading causes of death globally. The key factors in the pathogenesis of diabetes are …

Dysregulation of autophagy contributes to aging and to diseases such as
neurodegeneration, cardiomyopathy, and cancer. The paper by Yang et al.(2010) in this …

Significance: Alterations in adipose tissue function have profound consequences on whole
body energy homeostasis because this tissue is central for fat accumulation, energy …