Potential role of LPAR5 gene in prognosis and immunity of thyroid papillary carcinoma and pan-cancer

B Zhang, L Zhang, P Qi, R Pang, Z Wang, X Liu… - Scientific Reports, 2023 - nature.com
Papillary carcinomas account for the largest proportion of thyroid cancers, with papillary
thyroid carcinoma (PTC) being prone to early lymph node metastasis. Some studies have …

Downregulation of LPAR1 Promotes Invasive Behavior in Papillary Thyroid Carcinoma Cells

Z Bokaii Hosseini, F Rajabi… - Cancer …, 2024 - journals.sagepub.com
Background: Lysophosphatidic acid receptor 1 (LPAR1) has been identified as a biomarker
in various cancer types. However, its biological function in papillary thyroid carcinoma (PTC) …

[HTML][HTML] A novel prognostic biomarker LPAR6 in hepatocellular carcinoma via associating with immune infiltrates

J He, M Meng, H Wang - Journal of Clinical and Translational …, 2022 - ncbi.nlm.nih.gov
Methods The expression of LPAR6 and its clinical characteristics were evaluated on various
databases. The association between LPAR6 and immune infiltrates of various types of …

LPAR1, correlated with immune infiltrates, is a potential prognostic biomarker in prostate cancer

J Shi, D Jiang, S Yang, X Zhang, J Wang, Y Liu… - Frontiers in …, 2020 - frontiersin.org
Prostate cancer is a common malignancy in men worldwide. Lysophosphatidic acid receptor
1 (LPAR1) is a critical gene and it mediates diverse biologic functions in tumor. However, the …

LPAR5 promotes thyroid carcinoma cell proliferation and migration by activating class IA PI3K catalytic subunit p110β

WJ Zhao, LL Zhu, WQ Yang, SJ Xu, J Chen… - Cancer …, 2021 - Wiley Online Library
Abstract Lysophosphatidic acid receptor 5 (LPAR5) is involved in mediating thyroid cancer
progression, but the underlying mechanism needs to be further revealed. In this study, we …

LARP7 in papillary thyroid carcinoma induces NIS expression through suppression of the SHH signaling pathway

X Sui, Y Sui, Y Wang - Molecular medicine reports, 2018 - spandidos-publications.com
The incidence of thyroid cancer has increased the past few decades, the most frequent type
has been identified to be the papillary thyroid carcinoma (PTC). Following thyroidectomy …

LRRC52‐AS1 is associated with clinical progression and regulates cell migration and invasion in papillary thyroid cancer

Y Zhou, J Xiang, A Bhandari, J Wen… - Clinical and …, 2020 - Wiley Online Library
The incidence of thyroid cancer has increased in recent decades. The potential molecular
mechanisms of papillary thyroid cancer (PTC) are still to be uncovered. In recent years, a …

[HTML][HTML] Thyroid cancer prognostic biomarker ARL4A and its relationship with immune infiltration

X Han, J Liao, Y Zhou, X Hu, H Wu - International Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Thyroid cancer (THCA) is a prevalent form of cancer with high rates of
morbidity and mortality. The small GTPase ADP-ribosylation factor-like 4A (ARL4A) is …

LRP4 promotes proliferation, migration, and invasion in papillary thyroid cancer

X Zhou, E Xia, A Bhandari, C Zheng, J Xiang… - Biochemical and …, 2018 - Elsevier
Dysregulation of cell proliferation and death is considered the foundation of the malignant
biological characteristics of cancer. In this study, we conducted a comprehensive analysis of …

[HTML][HTML] Lysophosphatidic acid receptor 5 (LPAR5) plays a significance role in papillary thyroid cancer via phosphatidylinositol 3-kinase/Akt/mammalian target of …

CY Wu, C Zheng, EJ Xia, RD Quan, J Hu… - … Medical Journal of …, 2020 - ncbi.nlm.nih.gov
Lysophosphatidic Acid Receptor 5 (LPAR5) Plays a Significance Role in Papillary Thyroid
Cancer via Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (mTOR) …