Intergenerational transmission of stress in humans

ME Bowers, R Yehuda - Neuropsychopharmacology, 2016 - nature.com
The hypothesis that offspring are affected by parental trauma or stress exposure, first noted
anecdotally, is now supported empirically by data from Holocaust survivor offspring cohorts …

Transgenerational inheritance of stress pathology

SG Matthews, DI Phillips - Experimental neurology, 2012 - Elsevier
It is becoming increasingly evident that maternal exposure to adversity during pregnancy
leads to life-long effects in offspring. While there appears to be some commonality in the …

Development of individual differences in stress responsiveness: an overview of factors mediating the outcome of early life experiences

SEF Claessens, NP Daskalakis, R van der Veen… - …, 2011 - Springer
Rationale Human epidemiology and animal studies have convincingly shown the long-
lasting impact of early life experiences on the development of individual differences in stress …

Potential of environmental enrichment to prevent transgenerational effects of paternal trauma

K Gapp, J Bohacek, J Grossmann… - …, 2016 - nature.com
Adverse experiences in early life are risk factors for the development of behavioral and
physiological symptoms that can lead to psychiatric and cognitive disorders later in life …

Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

R Yehuda, A Lehrner - World psychiatry, 2018 - Wiley Online Library
This paper reviews the research evidence concerning the intergenerational transmission of
trauma effects and the possible role of epigenetic mechanisms in this transmission. Two …

Research review: intergenerational transmission of disadvantage: epigenetics and parents' childhoods as the first exposure

P Scorza, CS Duarte, AE Hipwell… - Journal of Child …, 2019 - Wiley Online Library
Background For decades, economists and sociologists have documented intergenerational
transmission of socioeconomic disadvantage, demonstrating that economic, political, and …

Sex differences in the programming effects of prenatal stress on psychopathology and stress responses: an evolutionary perspective

V Glover, J Hill - Physiology & behavior, 2012 - Elsevier
There is strong evidence from animal studies that prenatal stress has different effects on
male and female offspring. In general, although not always, prenatal stress increases …

Paternal transmission of stress-induced pathologies

DM Dietz, Q LaPlant, EL Watts, GE Hodes, SJ Russo… - Biological …, 2011 - Elsevier
BACKGROUND: There has been recent interest in the possibility that epigenetic
mechanisms might contribute to the transgenerational transmission of stress-induced …

Offspring psychological and biological correlates of parental posttraumatic stress: Review of the literature and research agenda

EW Leen-Feldner, MT Feldner, A Knapp… - Clinical psychology …, 2013 - Elsevier
Millions of individuals with posttraumatic stress disorder (PTSD) are parents. A burgeoning
literature suggests that offspring of parents with this condition may be at increased risk for …

Sex differences in vulnerability and resilience to stress across the life span

GE Hodes, CN Epperson - Biological psychiatry, 2019 - Elsevier
Susceptibility and resilience to stress depend on 1) the timing of the exposure with respect to
development, 2) the time across the life span at which effects are measured, and 3) the …