Introduction: Drug delivery systems (DDSs) are important for effective, safe, and convenient
administration of drugs. pH-and ion-responsive polymers have been widely employed in …

There are different pH-sensitive systems for biomedical applications that have recently been
considered for pH targeting nanomedicine. In this review, we examine some of the most …

Various pH-sensitive polymers have been developed for biomedical applications and
recently attracted much attention for pH targeting nanomedicine. Recent development of pH …

Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

The complexity of the tumor microenvironment presents significant challenges to cancer
therapy, while providing opportunities for targeted drug delivery. Using characteristic signals …

Polymer–drug conjugates are becoming established as a shining platform for drug delivery.
Incorporation of pH-responsive linker between drug and polymer is expected to realize …

Oral administration is a desirable alternative of parenteral administration due to the
convenience and increased compliance to patients, especially for chronic diseases that …

Use of macromolecular water-soluble carriers of anti-cancer drugs represents a promising
approach to cancer therapy. Release of drugs from the carrier system is a prerequisite for …

Stimuli‐responsive nanoparticles have the potential to improve the delivery of therapeutics
to a specific cell or region within the body. There are many stimuli that have shown potential …

Stimuli-responsive polymeric drug delivery systems using various triggers to release the
drug at the sites have become a major focus area. Among various stimuli-responsive …