Carcinogenesis is a several years to decades long process expressed in progressive
genetic changes and corresponding increasingly severe tissue damage (Figure 1). Cancer …

The prevention of cancer is one of the most important public health and medical practices of
the 21st century. We have made much progress in this new emerging field, but so much …

The aim of cancer chemoprevention is disruption or delay of the molecular pathways that
lead to carcinogenesis. Chemopreventive blocking and/or suppressing agents disrupt the …

Despite significant advances in cancer treatment and measures of neoplastic progression,
drug effect (or early detection, overall cancer incidence has increased, pharmacodynamic …

Chemoprevention—the use of natural or synthetic chemical agents to reverse, suppress, or
prevent progression to invasive cancer—is a major approach comprising laboratory and …

Cancer chemoprevention is the inhibition or reversal of carcinogenesis (before invasion) by
intervention with pharmacologically active agents. While minimizing exposure to …

The incidence and mortality rates for most of the common forms of cancer are still
unacceptably high. This stark fact in itself is a strong argument for further research, both …

As incoming President of the American Association for Cancer Research (AACR), I am
delighted that the AACR publishes the journal Cancer Prevention Research and that this …

Investigating the effects of potential preventive interventions is a central goal in cancer
preventive research. Elimination of proven risk-inducing exposures, such as tobacco, offers …

As cells progress through carcinogenesis, the associated exponential expansion of genetic
and molecular aberrations and resultant heterogeneity make therapeutic success …