Despite a substantial appreciation for the critical role of macrophages in cardiometabolic
diseases, understanding of human macrophage biology has been hampered by the lack of …

Rationale: An efficient and reproducible source of genotype-specific human macrophages is
essential for study of human macrophage biology and related diseases. Objective: To …

Macrophages play important roles in many diseases. We describe a protocol and the
associated resources for the differentiation of human induced pluripotent stem cell‐derived …

Macrophages are pivotal effectors of host immunity and regulators of tissue homeostasis.
Understanding of human macrophage biology has been hampered by the lack of reliable …

Macrophages differentiated from human induced pluripotent stem cells (IPSDMs) are a
potentially valuable new tool for linking genotype to phenotype in functional studies …

Macrophages are present in most vertebrate tissues and comprise widely dispersed and
heterogeneous cell populations with different functions. They are key players in health and …

Macrophages are immune cells with important roles in tissue homeostasis, inflammation and
pathologies. Hence, macrophage populations represent promising targets for modern …

Macrophages (Mφ) derived from induced pluripotent stem cells (iMphs) represent a novel
and promising model for studying human Mφ function and differentiation and developing …

Induced pluripotent stem cells (iPSC) offer the possibility to generate diverse disease-
relevant cell types, from any genetic background with the use of cellular reprogramming and …

Human induced pluripotent stem cells (iPSCs) and macrophages derived from them are
increasingly popular tools for research into both infectious and degenerative diseases …