Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

With the widespread use and sometimes even abuse of antibiotics, the problem of bacterial
resistance to antibiotics has become very serious, and it is posing a great threat to global …

Antibiotics are commonly used to fight against bacterial infections, but bacteria have already
been resistant to almost all antibiotics due to abuse of antibiotics. 1, 2, 4-Triazole derived …

The global spread of drug resistance in bacteria requires new potent and safe antimicrobial
agents. Compounds containing the 1, 2, 4-triazole ring in their structure are characterised by …

Research and development for novel substances possessing anti-infective activity have
attracted considerable attention due to the escalating resistance towards conventional …

Over the past few decades, the dynamic progress in the synthesis and screening of
heterocyclic compounds against various targets has made a significant contribution in the …

ESKAPE pathogens, as priority 1 and 2 pathogens, are prevalent infectious agents
associated with high morbidity and mortality. ESKAPE can cause broad-spectrum diseases …

Bacterial infections, caused predominately by Gram-positive and Gram-negative organisms,
are proliferation of harmful strains of bacteria on or inside the body. Hospital-acquired and …

Methicillin-resistant Staphylococcus aureus (MRSA), as a classic reason for genuine skin
and flimsy tissues diseases, is a worldwide general wellbeing risk and has already …

The present review aims to summarize the pharmacological profile of 1, 2, 4-triazole, one of
the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant …