The harsh urine microenvironment (UME), as an inherent hurdle, endangers and renders
urethral repair unreachable. Innovatively, the unfavorable UME is utilized as the design …

The harsh urethral microenvironment (UME) after trauma severely hinders the current
hydrogel-based urethral repair. In fact, four-dimensional (4D) consideration to mimic time …

Developing effective internal wound dressing materials is important for postoperative tissue
regeneration while remains a challenge due to the poor biological environment-adaptability …

In this study, ion-responsive hydrogen bonding strengthened hydrogels (termed as PVV)
were synthesized by one-pot copolymerization of 2-vinyl-4, 6-diamino-1, 3, 5-triazine (VDT) …

Rapid and effective repair of injured or diseased bone defects remains a major challenge
due to shortages of implants. Smart hydrogels that respond to internal and external stimuli to …

Dynamic stability and self-healing ability are two inherently compatible properties for living
organisms. By contrast, kinetic stability and intrinsic healability are two desired but mostly …

Several congenital and acquired conditions may result in severe narrowing of the urethra in
men, which represent an ongoing surgical challenge and a significant burden on both health …

The traditional hydrogels are prone to break due to the applied stress. The deformation of
the implanted hydrogels would result in the loss of structural integrity, leading to the failure of …

Recently, biomedicine and tissue regeneration have emerged as great advances that
impacted the spectrum of healthcare. This left the door open for further improvement of their …

Addressing the conflict between achieving high mechanical properties and room-
temperature self-healing ability is extremely significant to achieving a breakthrough in the …