[HTML][HTML] Effects of environmental steroid mixtures are regulated by individual steroid receptor signaling

S Schmid, RA Willi, K Fent - Aquatic Toxicology, 2020 - Elsevier
Fish are exposed to steroids of different classes in contaminated waters, but their effects are
not sufficiently understood. Here we employed an anti-sense technique using morpholino …

Physiological and transcriptional effects of mixtures of environmental estrogens, androgens, progestins, and glucocorticoids in zebrafish

RA Willi, S Castiglioni… - … science & technology, 2019 - ACS Publications
Fishes are exposed to mixtures of different classes of steroids, but ecotoxicological
implications are not sufficiently known. Here, we systematically analyze effects of different …

Transcriptional effects of androstenedione and 17α-hydroxyprogesterone in zebrafish embryos

K Fent, PF Siegenthaler, AA Schmid - Aquatic Toxicology, 2018 - Elsevier
Steroid hormones in the aquatic environment may pose a risk to fish health. Here we
evaluated effects of two different class steroids that frequently occur in the aquatic …

[HTML][HTML] Effects of the glucocorticoid clobetasol propionate and its mixture with cortisol and different class steroids in adult female zebrafish

S Faltermann, T Hettich, N Küng, K Fent - Aquatic Toxicology, 2020 - Elsevier
Ecotoxicological effects of glucocorticoids and steroid mixtures in the environment are not
sufficiently known. Here we investigate effects of 11–14 days exposure of female zebrafish …

Environmental glucocorticoids corticosterone, betamethasone and flumethasone induce more potent physiological than transcriptional effects in zebrafish embryos

RA Willi, N Salgueiro-González, S Faltermann… - Science of the Total …, 2019 - Elsevier
Many glucocorticoids occur in the aquatic environments but their adverse effects to fish are
poorly known. Here we investigate effects of the natural glucocorticoid corticosterone and …

Corticosteroid Fludrocortisone Acetate Targets Multiple End Points in Zebrafish (Danio rerio) at Low Concentrations

Y Zhao, K Zhang, K Fent - Environmental science & technology, 2016 - ACS Publications
Synthetic corticosteroids may pose an environmental risk to fish. Here, we describe multiend
point responses of adult zebrafish (8 months old) upon 21-day exposure to a commonly …

Active glucocorticoids have a range of important adverse developmental and physiological effects on developing zebrafish embryos

RA Willi, S Faltermann, T Hettich… - Environmental science & …, 2018 - ACS Publications
Glucocorticoids in aquatic systems originating from natural excretion and medical use may
pose a risk to fish. Here, we analyzed physiological and transcriptional effects of clobetasol …

Effects of new generation progestins, including as mixtures and in combination with other classes of steroid hormones, on zebrafish early life stages

S Schmid, RA Willi, N Salgueiro-González… - Science of The Total …, 2020 - Elsevier
Fish are exposed to progestins and steroid mixtures in contaminated waters but the
ecotoxicological implications are not sufficiently known. Here we analyze effects of the new …

Prednisolone Accelerates Embryonic Development of Zebrafish via Glucocorticoid Receptor Signaling at Low Concentrations

C Wang, M Li, W Gui, H Shi, P Wang… - Environmental …, 2023 - ACS Publications
Synthetic glucocorticoids have been widely detected in aquatic ecosystems and may pose a
toxicological risk to fish. In the present study, we described multiple end point responses of …

Detection of environmental glucocorticoids and investigation of their effects using the zebrafish embryo as a model

AO Hidasi - 2016 - infoscience.epfl.ch
Synthetic glucocorticoids (GCs) are widely used anti-inflammatory drugs. They mimic
cortisol, the natural stress hormone in humans and in fish. Cortisol binds and activates the …