Coupled electrophysiological, hemodynamic, and cerebrospinal fluid oscillations in human sleep

NE Fultz, G Bonmassar, K Setsompop, RA Stickgold… - Science, 2019 - science.org
Sleep is essential for both cognition and maintenance of healthy brain function. Slow waves
in neural activity contribute to memory consolidation, whereas cerebrospinal fluid (CSF) …

The interconnected causes and consequences of sleep in the brain

LD Lewis - Science, 2021 - science.org
Sleep is essential for brain function in a surprisingly diverse set of ways. In the short term,
lack of sleep leads to impaired memory and attention; in the longer term, it produces …

Brain neural patterns and the memory function of sleep

G Girardeau, V Lopes-dos-Santos - Science, 2021 - science.org
Sleep is crucial for healthy cognition, including memory. The two main phases of sleep, REM
(rapid eye movement) and non-REM sleep, are associated with characteristic …

Sleep drives metabolite clearance from the adult brain

L Xie, H Kang, Q Xu, MJ Chen, Y Liao, M Thiyagarajan… - science, 2013 - science.org
The conservation of sleep across all animal species suggests that sleep serves a vital
function. We here report that sleep has a critical function in ensuring metabolic homeostasis …

Breakdown of cortical effective connectivity during sleep

M Massimini, F Ferrarelli, R Huber, SK Esser, H Singh… - Science, 2005 - science.org
When we fall asleep, consciousness fades yet the brain remains active. Why is this so? To
investigate whether changes in cortical information transmission play a role, we used …

A cognitive process occurring during sleep is revealed by rapid eye movements

Y Senzai, M Scanziani - Science, 2022 - science.org
Since the discovery of rapid eye movement (REM) sleep, the nature of the eye movements
that characterize this sleep phase has remained elusive. Do they reveal gaze shifts in the …

Burst spiking of a single cortical neuron modifies global brain state

CT Li, M Poo, Y Dan - Science, 2009 - science.org
Different global patterns of brain activity are associated with distinct arousal and behavioral
states of an animal, but how the brain rapidly switches between different states remains …

Thalamocortical oscillations in the sleeping and aroused brain

M Steriade, DA McCormick, TJ Sejnowski - Science, 1993 - science.org
Sleep is characterized by synchronized events in billions of synaptically coupled neurons in
thalamocortical systems. The activation of a series of neuromodulatory transmitter systems …

Human REM sleep recalibrates neural activity in support of memory formation

JD Lendner, N Niethard, BA Mander… - Science …, 2023 - science.org
The proposed mechanisms of sleep-dependent memory consolidation involve the overnight
regulation of neural activity at both synaptic and whole-network levels. Now, there is a lack …

Why do we sleep?

TJ Sejnowski, A Destexhe - Brain research, 2000 - Elsevier
Slow-wave sleep consists in slowly recurring waves that are associated with a large-scale
spatio-temporal synchrony across neocortex. These slow-wave complexes alternate with …