[HTML][HTML] Emerging functions of tissue-resident eosinophils
A Gurtner, D Crepaz, IC Arnold - Journal of Experimental Medicine, 2023 - rupress.org
Eosinophils are typically considered tissue-damaging effector cells in type 2 immune-related
diseases. However, they are also increasingly recognized as important modulators of …
diseases. However, they are also increasingly recognized as important modulators of …
[HTML][HTML] Heterogeneity of intestinal tissue eosinophils: potential considerations for next-generation eosinophil-targeting strategies
JC Masterson, C Menard-Katcher, LD Larsen… - Cells, 2021 - mdpi.com
Eosinophils are implicated in the pathophysiology of a spectrum of eosinophil-associated
diseases, including gastrointestinal eosinophilic diseases (EGIDs). Biologics that target the …
diseases, including gastrointestinal eosinophilic diseases (EGIDs). Biologics that target the …
[HTML][HTML] The emerging role of eosinophils as multifunctional leukocytes in health and disease
HJ Kim, YJ Jung - Immune network, 2020 - ncbi.nlm.nih.gov
Eosinophils are terminally differentiated cytotoxic effector cells that have a role in parasitic
infections and allergy by releasing their granule-derived cytotoxic proteins. However, an …
infections and allergy by releasing their granule-derived cytotoxic proteins. However, an …
Spatial adaptation of eosinophils and their emerging roles in homeostasis, infection and disease
Eosinophils are bone marrow-derived granulocytes that are traditionally associated with
type 2 immune responses, such as those that occur during parasite infections and allergy …
type 2 immune responses, such as those that occur during parasite infections and allergy …
Functions of tissue-resident eosinophils
PF Weller, LA Spencer - Nature Reviews Immunology, 2017 - nature.com
Eosinophils are a prominent cell type in particular host responses such as the response to
helminth infection and allergic disease. Their effector functions have been attributed to their …
helminth infection and allergic disease. Their effector functions have been attributed to their …
Intestinal eosinophils: multifaceted roles in tissue homeostasis and disease
G . Coakley, H . Wang, NL . Harris - Seminars in Immunopathology, 2021 - Springer
Intestinal eosinophils are largely considered to be one of the central immune effector cells
during helminth infection and disorders such as eosinophilic oesophagitis and food …
during helminth infection and disorders such as eosinophilic oesophagitis and food …
Nutrient-derived signals regulate eosinophil adaptation to the small intestine
V I. Kutyavin, LL Korn… - Proceedings of the …, 2024 - National Acad Sciences
Eosinophils are well recognized as effector cells of type 2 immunity, yet they also
accumulate in many tissues under homeostatic conditions. However, the processes that …
accumulate in many tissues under homeostatic conditions. However, the processes that …
Roles and regulation of gastrointestinal eosinophils in immunity and disease
YJ Jung, ME Rothenberg - The Journal of Immunology, 2014 - journals.aai.org
Eosinophils have historically been considered to be destructive end-stage effector cells that
have a role in parasitic infections and allergic reactions by the release of their granule …
have a role in parasitic infections and allergic reactions by the release of their granule …
Common γ-chain-dependent signals confer selective survival of eosinophils in the murine small intestine
J Carlens, B Wahl, M Ballmaier… - The Journal of …, 2009 - journals.aai.org
Eosinophils are potent effector cells that are recruited to sites of inflammation. However, in
some tissues, in particular in the gastrointestinal tract, eosinophils constitute an abundant …
some tissues, in particular in the gastrointestinal tract, eosinophils constitute an abundant …
[HTML][HTML] Eosinophils in mucosal immune responses
J Travers, ME Rothenberg - Mucosal immunology, 2015 - Elsevier
Eosinophils, multifunctional cells that contribute to both innate and adaptive immunity, are
involved in the initiation, propagation, and resolution of immune responses, including tissue …
involved in the initiation, propagation, and resolution of immune responses, including tissue …