Abstract Schizophrenia affects> 3.2 million people in the USA. However, its comorbidity
patterns have not been systematically characterized in real-world populations. To address …

Schizophrenia is a chronic debilitating psychiatric disorder with significant morbidity and
mortality. In this study, we used information from 337,484 UK Biobank participants and …

Background The burden associated with schizophrenia is substantial. Impacts on the
individual, healthcare system, and society may be particularly striking within the veteran …

Importance Although early mortality in severe psychiatric illness is linked to smoking and
alcohol, to our knowledge, no studies have comprehensively characterized substance use …

Schizophrenia is a heterogeneous disorder, exhibiting variability in presentation and
outcomes that complicate treatment and recovery. To explore this heterogeneity, we …

BACKGROUND: Persons with persistent mental illness are at risk for failure to receive
medical services. In order to deliver appropriate preventive and primary care for this …

Background Genome-wide association studies (GWAS) have identified several loci
associated with schizophrenia and/or bipolar disorder. We performed a GWAS of psychosis …

Importance Serious mental illnesses, including schizophrenia, bipolar disorder, and
depression, are heritable, highly multifactorial disorders and major causes of disability …

Introduction Many patients exhibit subsyndromal clinical findings of schizophrenia prior to
diagnosis. Early treatment may mitigate schizophrenia development, yet little is known about …

Schizophrenia is a serious mental disorder with considerable somatic and psychiatric
morbidity. It is unclear whether comorbid health conditions predominantly arise due to …