Recent developments on synthesis strategies, SAR studies and biological activities of β-carboline derivatives–an update

R Abinaya, S Srinath, S Soundarya, R Sridhar… - Journal of Molecular …, 2022 - Elsevier
The β-carboline skeleton is prevalent in a vast collection of naturally present alkaloids. Most
of these alkaloids and their derivatives have been found to show significant biological …

β-Carboline alkaloid monomers and dimers: Occurrence, structural diversity, and biological activities

J Dai, W Dan, U Schneider, J Wang - European journal of medicinal …, 2018 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with great
structural diversity and outstanding biological activities. This review covers critically …

A comprehensive overview of β-carbolines and its derivatives as anticancer agents

B Luo, X Song - European Journal of Medicinal Chemistry, 2021 - Elsevier
Abstract β-Carboline alkaloids are a family of natural and synthetic products with structural
diversity and outstanding antitumor activities. This review summarizes research …

Recent advances in the synthesis of β-carboline alkaloids

T Szabó, B Volk, M Milen - Molecules, 2021 - mdpi.com
β-Carboline alkaloids are a remarkable family of natural and synthetic indole-containing
heterocyclic compounds and they are widely distributed in nature. Recently, these alkaloids …

Recent developments on synthesis and biological activities of γ-carboline

J Dai, W Dan, Y Zhang, J Wang - European journal of medicinal chemistry, 2018 - Elsevier
Abstract γ-Carboline alkaloids are a family of natural and synthetic agents that have diverse
bioactivities including antiviral, antibacterial, antifungal, antiparasitic, antitumor, anti …

Inspired by bis-β-carboline alkaloids: Construction and antitumor evaluation of a novel bis-β-carboline scaffold as potent antitumor agents

W Liu, M Wang, Z Guo, Y He, H Jia, J He, S Miao… - Bioorganic …, 2023 - Elsevier
Bis-β-carboline alkaloids are widely distributed in natural products and represent a
promising drug-like scaffold for discovering drugs and bioactive molecules. In this study, we …

β-Carbolines as potential anticancer agents

S Aaghaz, K Sharma, R Jain, A Kamal - European Journal of Medicinal …, 2021 - Elsevier
Abstract β-Carbolines are indole alkaloids having a tricyclic pyrido [3, 4-b] indole ring in their
structure. Since the isolation of first β-carboline from Peganum harmala in 1841, the isolation …

Recent advances of natural and synthetic β-carbolines as anticancer agents

M Zhang, D Sun - Anti-Cancer Agents in Medicinal Chemistry …, 2015 - ingentaconnect.com
Cancer is a leading cause of mortality worldwide, being responsible for millions of deaths
annually. Therefore, novel cancer chemotherapeutic agents are urgently needed to combat …

[HTML][HTML] Beta-carboline as a promising heterocyclic nucleus: Synthetic aspects, pharmacological potential and structure activity relationship

M Thatikayala, P Wadhwa, P Kaur, PK Singh… - European Journal of …, 2022 - Elsevier
Beta-carboline is an indole alkaloid which has been identified as a valuable heterocyclic
nucleus in the field of medicinal chemistry. It has different biological activities like …

Recent Update on the Anti-infective Potential of β-carboline Analogs

BK Kumar, KVGC Sekhar, S Kunjiappan… - Mini reviews in …, 2021 - ingentaconnect.com
β-Carboline, a naturally occurring indole alkaloid, holds a momentous spot in the field of
medicinal chemistry due to its myriad of pharmacological actions like anticancer, antiviral …