Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability

M Khalid, SH Alamri, HH Alsulimani, WS Alharbi… - International Journal of …, 2023 - Elsevier
Valsartan (VST) is a poorly soluble antihypertensive drug characterized by its limited
dissolution rate and low bioavailability. This study aims to improve VST solubility and …

Development, optimization, and characterization of solid self-nanoemulsifying drug delivery systems of valsartan using porous carriers

S Beg, S Swain, HP Singh, CN Patra, MEB Rao - Aaps Pharmscitech, 2012 - Springer
The present studies entail formulation development of novel solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) of valsartan with improved oral bioavailability, and evaluation …

Development of self-nanoemulsifying drug delivery system for oral bioavailability enhancement of valsartan in beagle dogs

Z Li, W Zhang, Y Gao, R Xiang, Y Liu, M Hu… - Drug delivery and …, 2017 - Springer
Valsartan, an angiotensin II receptor antagonist, is widely used to treat high blood pressure
in the clinical setting. However, its poor water solubility results in the low oral bioavailability …

The development of self-nanoemulsifying liquisolid tablets to improve the dissolution of simvastatin

S Elkadi, S Elsamaligy, S Al-Suwayeh… - AAPS PharmSciTech, 2017 - Springer
The aim of this work was to develop self-nanoemulsifying liquisolid tablets (SNELT) to
enhance the dissolution profile of poorly water-soluble simvastatin. SNELT present a unique …

[HTML][HTML] Systematic development of self-nanoemulsifying liquisolid tablets to improve the dissolution and oral bioavailability of an oily drug, vitamin K1

Y Tong, Y Wang, M Yang, J Yang, L Chen, X Chu… - Pharmaceutics, 2018 - mdpi.com
The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug,
vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The …

[PDF][PDF] Self-nanoemulsifying drug delivery systems of Valsartan: preparation and in-vitro characterization

PS Rajinikanth, NW Keat, S Garg - International journal of drug delivery, 2012 - core.ac.uk
The main objective this study is to prepare and evaluate the selfnanoemulsifying drug
delivery (SNEDDS) system in order to achieve a better dissolution rate of a poorly water …

Preparation and evaluation of valsartan by a novel semi-solid self-microemulsifying delivery system using Gelucire 44/14

K Zhao, Y Yuan, H Wang, P Li, Z Bao… - Drug Development and …, 2016 - Taylor & Francis
The aim of the present study was to develop a novel semi-solid self-microemulsifying drug
delivery system (SMEDDS) using Gelucire® 44/14 as oil with strong solid character to …

Solid self-nanoemulsifying systems of olmesartan medoxomil: Formulation development, micromeritic characterization, in vitro and in vivo evaluation

S Beg, OP Katare, S Saini, B Garg, RK Khurana… - Powder technology, 2016 - Elsevier
The current studies entail development and evaluation of solid self-nanoemulsifying drug
delivery systems (S-SNEDDS) employing porous carriers for enhancing the oral …

Development and in vitro characterization of self-nanoemulsifying drug delivery systems of valsartan

PS Rajinikanth, Y Suyu, S Garg - International Journal of …, 2012 - publications.waset.org
The present study is aim to prepare and evaluate the selfnanoemulsifying drug delivery
(SNEDDS) system of a poorly water soluble drug valsartan in order to achieve a better …

Formulation of self-nanoemulsifying drug delivery system for telmisartan with improved dissolution and oral bioavailability

J Ahmad, K Kohli, SR Mir, S Amin - Journal of Dispersion Science …, 2011 - Taylor & Francis
To improve the dissolution and oral absorption of poorly water soluble drug-telmisartan, a
self-nanoemulsifying system (SNES) was developed, characterized, and its relative …