Thousands of previously unknown phages discovered in whole-community human gut metagenomes
Background Double-stranded DNA bacteriophages (dsDNA phages) play pivotal roles in
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
structuring human gut microbiomes; yet, the gut virome is far from being fully characterized …
[HTML][HTML] Massive expansion of human gut bacteriophage diversity
LF Camarillo-Guerrero, A Almeida, G Rangel-Pineros… - Cell, 2021 - cell.com
Bacteriophages drive evolutionary change in bacterial communities by creating gene flow
networks that fuel ecological adaptions. However, the extent of viral diversity and its …
networks that fuel ecological adaptions. However, the extent of viral diversity and its …
A highly abundant bacteriophage discovered in the unknown sequences of human faecal metagenomes
Metagenomics, or sequencing of the genetic material from a complete microbial community,
is a promising tool to discover novel microbes and viruses. Viral metagenomes typically …
is a promising tool to discover novel microbes and viruses. Viral metagenomes typically …
Genome signature-based dissection of human gut metagenomes to extract subliminal viral sequences
LA Ogilvie, LD Bowler, J Caplin, C Dedi… - Nature …, 2013 - nature.com
Bacterial viruses (bacteriophages) have a key role in shaping the development and
functional outputs of host microbiomes. Although metagenomic approaches have greatly …
functional outputs of host microbiomes. Although metagenomic approaches have greatly …
Classification and quantification of bacteriophage taxa in human gut metagenomes
Bacteriophages have key roles in microbial communities, to a large extent shaping the
taxonomic and functional composition of the microbiome, but data on the connections …
taxonomic and functional composition of the microbiome, but data on the connections …
Probing the “dark matter” of the human gut phageome: Culture assisted metagenomics enables rapid discovery and host-linking for novel bacteriophages
CB Fitzgerald, AN Shkoporov, A Upadrasta… - Frontiers in cellular …, 2021 - frontiersin.org
Recent years have been marked by the growing interest towards virulent and temperate
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …
bacteriophage populations inhabiting the human lower gastrointestinal tract–the gut …
Bacteroides thetaiotaomicron-infecting bacteriophage isolates inform sequence-based host range predictions
Our emerging view of the gut microbiome largely focuses on bacteria, while less is known
about other microbial components, such as bacteriophages (phages). Though phages are …
about other microbial components, such as bacteriophages (phages). Though phages are …
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome
Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …
under-represented in reference databases. To address this problem, we assembled the …
Diversity, evolution, and classification of virophages uncovered through global metagenomics
Background Virophages are small viruses with double-stranded DNA genomes that
replicate along with giant viruses and co-infect eukaryotic cells. Due to the paucity of …
replicate along with giant viruses and co-infect eukaryotic cells. Due to the paucity of …
Shining light on human gut bacteriophages
E Guerin, C Hill - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The human gut is a complex environment that contains a multitude of microorganisms that
are collectively termed the microbiome. Multiple factors have a role to play in driving the …
are collectively termed the microbiome. Multiple factors have a role to play in driving the …