Appropriate autophagy has protective effects on ischemic nerve tissue, while excessive
autophagy may cause cell death. The inflammatory response plays an important role in the …

Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …

Evidence suggests that autophagy may be a new therapeutic target for stroke, but whether
activation of autophagy increases or decreases the rate of neuronal death is still under …

Cerebral ischemia is a severe outcome that could cause cognitive and motor dysfunction,
neurodegenerative diseases and even acute death. Although the existence of autophagy in …

With the use of advanced electron microscopy and molecular biology tools, several studies
have shown that autophagy is involved in the development of ischemic stroke. A series of …

Autophagy is a strictly regulated process that degrades and recycles long-lived or misfolded
proteins and damaged organelles for the maintenance of energy and function homeostasis …

There is increasing evidence indicating that autophagy may be a new target in the treatment
of ischemic stroke. Moderate autophagy can clear damaged organelles, thereby protecting …

Although many attempts have been made, stroke treatment options are still extremely limited
and brain ischemia remains the leading cause of death and disability worldwide. Two major …

Stroke is one of the leading causes of death and disability worldwide. Autophagy is a
conserved cellular catabolic pathway that maintains cellular homeostasis by removal of …

Ischemic stroke refers to brain tissue ischemia, hypoxic necrosis, and brain softening caused
by the interruption of the blood supply to the brain without adequate collateral circulation …