[HTML][HTML] Cerebrospinal fluid oligoclonal immunoglobulin gamma bands and long-term disability progression in multiple sclerosis: a retrospective cohort study

VD Karrenbauer, SK Bedri, J Hillert… - Scientific Reports, 2021 - nature.com
Multiple sclerosis (MS) patients with immunoglobulin gamma (IgG) oligoclonal bands (OCB)
in the cerebrospinal fluid (CSF) have different genetic backgrounds and brain MRI features …

[HTML][HTML] Increased cortical lesion load and intrathecal inflammation is associated with oligoclonal bands in multiple sclerosis patients: a combined CSF and MRI study

G Farina, R Magliozzi, M Pitteri, R Reynolds… - Journal of …, 2017 - Springer
Abstract Background Although IgG oligoclonal bands (OCBs) in the cerebrospinal fluid
(CSF) are a frequent phenomenon in multiple sclerosis (MS) patients, their relationship with …

[HTML][HTML] Absence of Oligoclonal Bands in Multiple Sclerosis: A Call for Differential Diagnosis

E Katsarogiannis, AM Landtblom… - Journal of Clinical …, 2023 - mdpi.com
Background: Immunoglobulin gamma (IgG) oligoclonal bands (OCB) in the cerebrospinal
fluid (CSF) are absent in a small group of multiple sclerosis (MS) patients. According to …

Cerebrospinal fluid immunological biomarkers associated with axonal damage in multiple sclerosis

LM Villar, C Picón, L Costa‐Frossard… - European journal of …, 2015 - Wiley Online Library
Background and purpose Cerebrospinal fluid (CSF) neurofilament light protein (NFL) is a
promising biomarker of axonal injury and neurodegeneration. Here CSF lymphocyte …

Immunoglobulin M oligoclonal bands: biomarker of targetable inflammation in primary progressive multiple sclerosis

LM Villar, B Casanova, N Ouamara… - Annals of …, 2014 - Wiley Online Library
Objective To identify a biomarker distinguishing patients who, despite a primary progressive
multiple sclerosis (PPMS) clinical course, may nonetheless benefit from immune therapy …

Oligoclonal IgM bands in the cerebrospinal fluid of patients with relapsing MS to inform long-term MS disability

R Capuano, I Zubizarreta… - Multiple Sclerosis …, 2021 - journals.sagepub.com
Background: Prognostic markers are needed to guide multiple sclerosis (MS) management
in the context of large availability of disease-modifying drugs (DMDs). Objective: To …

Oligoclonal bands and cerebrospinal fluid markers in multiple sclerosis: associations with disease course and progression

P Lourenco, A Shirani, J Saeedi, J Oger… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: The use of oligoclonal bands (OCBs) and cerebrospinal fluid (CSF) parameters
are established in the diagnosis of MS, but poorly as markers of disease. Objective: To …

Oligoclonal bands in multiple sclerosis patients: worse prognosis?

JI Rojas*, S Tizio*, L Patrucco, E Cristiano - Neurological research, 2012 - Taylor & Francis
Introduction: Cerebrospinal fluid (CSF) oligoclonal bands (OB) imply intrathecal
immunoglobulin synthesis and B-cell immune process. There is scarce evidence of OB …

CSF oligoclonal band patterns reveal disease heterogeneity in multiple sclerosis

LM Villar, T Masterman, B Casanova… - Journal of …, 2009 - Elsevier
Oligoclonal IgG bands (OCGB) are characteristic of multiple sclerosis (MS). Most patients
show OCGB exclusively in cerebrospinal fluid (CSF). Others have serum bands with …

Association of intrathecal immunoglobulin G synthesis with disability worsening in multiple sclerosis

C Gasperi, A Salmen, G Antony, A Bayas… - JAMA …, 2019 - jamanetwork.com
Importance Reliable biomarkers associated with disability worsening in multiple sclerosis
(MS) are still needed. Objective To determine a possible association of intrathecal IgG …