Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for
which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 …

Abstract Viruses cause 10–15% of all human cancers. Massively parallel sequencing has
recently proved effective for uncovering novel viruses and virus–tumour associations, but …

Elucidation of tumor-DNA virus associations in many cancer types has enhanced our
knowledge of fundamental oncogenesis mechanisms and provided a basis for cancer …

We have developed a virus detection and discovery computational pipeline, Pickaxe, and
applied it to NGS databases provided by The Cancer Genome Atlas (TCGA). We analyzed a …

We applied a newly developed bioinformatics system called VirusScan to investigate the
viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types …

Telomerase plays a pivotal role in tumorigenesis by both telomere‐dependent and telomere‐
independent activities, although the underlying mechanisms are not completely understood …

Cancer cells survive cellular crisis through telomere maintenance mechanisms. We report
telomere lengths in 18,430 samples, including tumors and non-neoplastic samples, across …

Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …

Human papillomavirus (HPV) is a necessary but insufficient cause of a subset of oral
squamous cell carcinomas (OSCCs) that is increasing markedly in frequency. To identify …

Cell lines are important tools for biological and preclinical investigation, and establishing
their relationship to genomic alterations in tumors could accelerate functional and …