Outer hair cells (OHCs) are highly specialized sensory cells conferring the fine‐tuning and
high sensitivity of the mammalian cochlea to acoustic stimuli. Here, by genetically …

Key points Outer hair cells (OHCs) enhance the sensitivity and the frequency tuning of the
mammalian cochlea. Similar to the primary sensory receptor, the inner hair cells (IHCs), the …

Before the onset of hearing, which occurs around postnatal day 12 (P12) in mice, inner hair
cells (IHCs) of the immature cochlea generate sound-independent Ca2+ action potentials …

Before mice start to hear at approximately postnatal day 10, their cochlear inner hair cells
(IHCs) spontaneously generate Ca2+ action potentials. Therefore, immature IHCs could …

Outer hair cells (OHCs) are innervated by type II afferent fibers of as yet unknown function. It
is still a matter of debate whether OHCs perform exocytosis. If so, they would require …

During a critical developmental period, cochlear inner hair cells (IHCs) exhibit sensory-
independent activity, featuring action potentials in which Ca2+ ions play a fundamental role …

Sensory‐independent Ca2+ spiking regulates the development of mammalian sensory
systems. In the immature cochlea, inner hair cells (IHCs) fire spontaneous Ca2+ action …

Cochlear inner hair cells (IHCs) release neurotransmitter onto afferent auditory nerve fibers
in response to sound stimulation. Normal development and function of inner hair cells …

Hearing relies on faithful signal transmission by cochlear inner hair cells (IHCs) onto
auditory fibres over a wide frequency and intensity range. Exocytosis at IHC ribbon …

Outer hair cells (OHCs) amplify the sound-evoked motion of the basilar membrane to
enhance acoustic sensitivity and frequency selectivity. Medial olivocochlear (MOC) efferents …