This study focuses on the innovation of an inhaled sustained release form of insulin and the
development of a neuro-fuzzy model specifically tailored to predict insulin release kinetics …

A successful approach to designing an intelligent insulin delivery system could facilitate
diabetic patients' lives especially for type 1 diabetes. The aim of the present investigation …

Methods NIPAAm-MAA-HEM copolymers were synthesized by radical chain reaction with
86: 4: 10 (5% w/v) ratios respectively. Reaction was carried out in 1, 4-Dioxane under …

Diabetes mellitus type 1 (T1DM) is a form of diabetes mellitus that results from the
autoimmune destruction of the insulin producing β-cells in the pancreas. This study aims to …

The search for an effective and reliable oral insulin delivery system has been a major
challenge facing pharmaceutical scientists for over many decades. Even though …

Poly (diethylaminoethyl methacrylate-g-ethylene glycol) hydrogels were prepared having a
molar ratio of 10: 1 diethylaminoethyl methacrylate to poly (ethylene glycol) of molecular …

Insulin-loaded microspheres composed of chitosan 3%(w/v), and loading 120 IU insulin
were produced by emulsion cross-linking method. Cross-linking time was 5 h and …

In the recent years, temperature and pH-sensitive hydrogels were developed as suitable
carriers for drug delivery. In this study, four different pH-sensitive nanohydrogels were …

An injectable biodegradable hydrogel system based on oligo (amidoamine/β-amino
ester)(OAAAE) was designed and synthesized for controlled release of insulin under the …

A comprehensive parameter study is carried out in this paper for analysis of the influence of
the immobilized glucose oxidase (GOx) and catalase on the equilibrium response of a …