Radioembolisation (RE), with yttrium-90 (90Y) labelled microspheres, is an increasingly
common treatment method for unresectable liver tumours. The tolerable mean absorbed …

Background Selective arterial radioembolisation of liver tumours has increased, because of
encouraging efficacy reports; however, therapeutic parameters used in external beam …

The 50% normal-tissue complication probability (NTCP) after lobar irradiation of the liver
results in highly variable biologic effective doses depending on the modality used: a biologic …

Background The higher tolerated mean absorbed dose for selective internal radiation
therapy (SIRT) with intra-arterially infused 90 Y microspheres compared to external beam …

Selective internal radiation treatment (SIRT) via intrahepatic arterial administration of 90Y
microspheres is an effective therapeutic modality. The conventional and generally applied …

This article aims at presenting in a didactic way, dosimetry concepts and methods that are
relevant for radio-embolization of the liver with 90Y-microspheres. The application of the …

Radioembolization (RE) of liver cancer with 90Y-microspheres has been applied in the last
two decades with notable responses and acceptable toxicity. Two types of microspheres are …

Abstract Radioembolization (RE) with yttrium-90 (90Y) microspheres, a transcatheter
intraarterial therapy for patients with liver cancer, can be modeled computationally. The …

Introduction The model provided by manufacturers of the Y-90 microspheres does not
consider dose restrictions to tumor and to normal liver volumes, but simply calculates activity …

Dosimetry in liver radioembolization with 90 Y microspheres is a fundamental tool, both for
the optimization of each treatment and for improving knowledge of the treatment effects in …