Jintiange capsules ameliorate osteoarthritis by modulating subchondral bone remodeling and protecting cartilage against degradation

C Zhuang, Z Wang, W Chen, H Wang… - Frontiers in …, 2021 - frontiersin.org
Osteoarthritis (OA) is the most prevalent joint disease worldwide, making it a major cause of
pain and disability. Identified as a chronic and progressive disease, effective treatment at the …

Tougu Xiaotong capsule exerts a therapeutic effect on knee osteoarthritis by regulating subchondral bone remodeling

G Wu, J Zhang, W Chen, S Chen… - Molecular …, 2019 - spandidos-publications.com
Previous studies have shown that Tougu Xiaotong capsule (TGXTC) has therapeutic effects
on knee osteoarthritis (OA) through multiple targets. However, the mechanisms of action …

Jintiange capsule alleviates rheumatoid arthritis and reverses changes of serum metabolic profile in collagen-induced arthritic rats

X Wang, Y Shen, X Zhuang, N Wang… - Journal of …, 2021 - Taylor & Francis
Purpose Jintiange capsule (JTG), an approved drug developed as a substitute for tiger bone
(TB), has been clinically applied for osteoporosis therapy since 2003. The drug is composed …

Zhuifeng tougu capsules inhibit the TLR4/MyD88/NF-κB signaling pathway and alleviate knee osteoarthritis: In vitro and in vivo experiments

X Xu, N Li, Y Wu, K Yan, Y Mi, N Yi, X Tan… - Frontiers in …, 2022 - frontiersin.org
Background: Knee osteoarthritis (KOA), a chronic degenerative disease, is mainly
characterized by destruction of articular cartilage and inflammatory reactions. At present …

Bioactive components and potential mechanisms of Biqi Capsule in the treatment of osteoarthritis: based on chondroprotective and anti-inflammatory activity

Z Jia, J Zhang, X Yang, H Chen, Y Wang… - Frontiers in …, 2024 - frontiersin.org
Cartilage damage and synovial inflammation are vital pathological changes in osteoarthritis
(OA). Biqi Capsule, a traditional Chinese medicine formula used for the clinical treatment of …

Yougui pills attenuate cartilage degeneration via activation of TGF-β/Smad signaling in chondrocyte of osteoarthritic mouse model

L Zhang, P Wang, J Ying, X Jin, C Luo, T Xu… - Frontiers in …, 2017 - frontiersin.org
Yougui pills (YGPs) have been used for centuries in the treatment of Chinese patients with
Kidney-Yang Deficiency Syndrome. Despite the fact that the efficiency of YGPs on treating …

The protective effect of traditional Chinese medicine Jinteng Qingbi granules on rats with rheumatoid arthritis

Y Wan, W Sun, J Yang, H Wang, W Wang… - Frontiers in …, 2024 - frontiersin.org
Introduction: Jinteng Qingbi granules (JTQBG), a traditional Chinese medicine formulation,
are widely used for the treatment of rheumatoid arthritis (RA) due to their satisfactory …

[HTML][HTML] Network pharmacology integrated with experimental validation revealed the mechanism of Fengshi Gutong capsule in the treatment of osteoarthritis

Y Sun, J Liu, J Wang, M He, X Chen, L Chen - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Fengshi Gutong Capsule (FSGTC) is a commonly
used Chinese medicine for the treatment of joint pain caused by osteoarthritis (OA) …

Gubi Zhitong formula alleviates osteoarthritis in vitro and in vivo via regulating BNIP3L-mediated mitophagy

J Yang, Z Zhou, X Ding, R He, A Li, Y Wei, M Wang… - Phytomedicine, 2024 - Elsevier
Background Osteoarthritis (OA) is characterized by degeneration of articular cartilage,
leading to joint pain and dysfunction. Gubi Zhitong formula (GBZTF), a traditional Chinese …

[HTML][HTML] Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway

H Xia, D Cao, F Yang, W Yang, W Li, P Liu… - Biomedicine & …, 2020 - Elsevier
Jiawei Yanghe decoction (JWYHD) is a Traditional Chinese Medicine (TCM) formula for the
treatment of osteoarthritis (OA), however the underlying mechanisms of action of JWYHD in …