It is hypothesized that the ability to discriminate between threat and safety is impaired in
individuals with high dispositional negativity, resulting in maladaptive behavior. A large body …

It is hypothesized that the ability to discriminate between threat and safety is impaired in
individuals with high dispositional negativity, resulting in maladaptive behavior. A large body …

Background. Intolerance of uncertainty (IU) is a transdiagnostic risk factor for an array of
psychiatric disorders, and plays an important role in fear and threat learning. In concert, the …

Identifying individual differences in the ability to discriminate signals of threat and safety
holds great potential to elucidate etiological mechanisms of pathological anxiety and …

Individuals who score high in self-reported Intolerance of Uncertainty (IU) tend to find
uncertainty unacceptable and aversive. In recent years, research has shed light on the role …

Attending to stimuli that share perceptual similarity to learned threats is an adaptive strategy.
However, prolonged threat generalization to cues signalling safety is considered a core …

Impaired safety learning has been proposed as a risk factor for anxiety disorders, but safety
can be indicated by either threat absence or threat termination (ie, relief). Here, we …

Fear generalization is a key player in understanding why some individuals feel unsafe in
objectively non-threatening situations. Although fear is adaptive, it can persist when …

Extinction-resistant threat is considered to be a central feature of pathological anxiety.
Reduced threat extinction is observed in individuals with high intolerance of uncertainty (IU) …

Exposure therapy is at the core of the treatment of pathological anxiety. While the inhibitory
learning model proposes a framework for the mechanisms underlying exposure therapy, in …