Integrated molecular analysis of adult T cell leukemia/lymphoma

K Kataoka, Y Nagata, A Kitanaka, Y Shiraishi… - Nature …, 2015 - nature.com
Adult T cell leukemia/lymphoma (ATL) is a peripheral T cell neoplasm of largely unknown
genetic basis, associated with human T cell leukemia virus type-1 (HTLV-1) infection. Here …

Genetic alterations in adult T‐cell leukemia/lymphoma

Y Kogure, K Kataoka - Cancer science, 2017 - Wiley Online Library
Adult T‐cell leukemia/lymphoma (ATL) is a peripheral T‐cell neoplasm with a dismal
prognosis. It is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. A long …

Whole-genome landscape of adult T-cell leukemia/lymphoma

Y Kogure, T Kameda, J Koya… - Blood, The Journal …, 2022 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive neoplasm immunophenotypically
resembling regulatory T cells, associated with human T-cell leukemia virus type-1. Here, we …

Adult T-cell leukemia: molecular basis for clonal expansion and transformation of HTLV-1–infected T cells

T Watanabe - Blood, The Journal of the American Society of …, 2017 - ashpublications.org
Adult T-cell leukemia (ATL) is an aggressive T-cell malignancy caused by human T-cell
leukemia virus type 1 (HTLV-1) that develops through a multistep carcinogenesis process …

Prognostic relevance of integrated genetic profiling in adult T-cell leukemia/lymphoma

K Kataoka, M Iwanaga, J Yasunaga… - Blood, The Journal …, 2018 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is a heterogeneous group of peripheral T-cell
malignancies characterized by human T-cell leukemia virus type-1 infection, whose genetic …

[HTML][HTML] Chronological genome and single-cell transcriptome integration characterizes the evolutionary process of adult T cell leukemia-lymphoma

M Yamagishi, M Kubokawa, Y Kuze, A Suzuki… - Nature …, 2021 - nature.com
Subclonal genetic heterogeneity and their diverse gene expression impose serious
problems in understanding the behavior of cancers and contemplating therapeutic …

North American ATLL has a distinct mutational and transcriptional profile and responds to epigenetic therapies

UA Shah, EY Chung, O Giricz… - Blood, The Journal …, 2018 - ashpublications.org
Adult T-cell leukemia lymphoma (ATLL) is a rare T cell neoplasm that is endemic in
Japanese, Caribbean, and Latin American populations. Most North American ATLL patients …

The role of HTLV-1 clonality, proviral structure, and genomic integration site in adult T-cell leukemia/lymphoma

LB Cook, A Melamed, H Niederer… - Blood, The Journal …, 2014 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) occurs in∼ 5% of human T-lymphotropic virus type 1
(HTLV-1)–infected individuals and is conventionally thought to be a monoclonal disease in …

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma

L Jiang, ZH Gu, ZX Yan, X Zhao, YY Xie, ZG Zhang… - Nature …, 2015 - nature.com
Natural killer/T-cell lymphoma (NKTCL) is a malignant proliferation of CD56+ and cytoCD3+
lymphocytes with aggressive clinical course, which is prevalent in Asian and South …

Evolution of retrovirus-infected premalignant T-cell clones prior to adult T-cell leukemia/lymphoma diagnosis

AG Rowan, R Dillon, A Witkover… - Blood, The Journal …, 2020 - ashpublications.org
Adult T-cell leukemia/lymphoma (ATL) is an aggressive hematological malignancy caused
by human T-cell leukemia virus type-1 (HTLV-1). ATL is preceded by decades of chronic …