Age-associated decline in antioxidant potential and accumulation of reactive
oxygen/nitrogen species are primary causes for multiple health problems, including …

Age-related loss of skeletal muscle mass and contractile dysfunction, or sarcopenia, reduces
independence and quality of life in the elderly and leads to increased risk of comorbidities …

Skeletal muscle redox homeostasis is transcriptionally regulated by nuclear erythroid-2-p45-
related factor-2 (Nrf2). We recently demonstrated that age-associated stress impairs Nrf2 …

Oxidative stress and mitochondrial dysfunction are associated with the aging process.
However, the role of nuclear factor erythroid 2‐related factor 2 (Nrf2) in skeletal muscle …

Aging promotes accumulation of reactive oxygen/nitrogen species (ROS/RNS) in
cardiomyocytes, which leads to contractile dysfunction and cardiac abnormalities. These …

The progressive and generalized loss of skeletal muscle mass and function, also known as
sarcopenia, underlies disability, increasing adverse outcomes and poor quality of life in …

Oxidative stress‐induced mitochondrial dysfunction is associated with age‐related and
disuse‐induced skeletal muscle atrophy. However, the role of nuclear factor erythroid 2 …

The role of nuclear factor-erythroid 2 p45-related factor 2 (Nrf2) and Kelch-like ECH-
associated protein 1 (Keap1) redox signaling has not been characterized in human skeletal …

In recent years, growing evidence has suggested a prominent role of oxidative stress in the
pathophysiology of several early-and adult-onset muscle disorders, although effective …

Recently we have reported that age‐dependent decline in antioxidant levels accelerated
apoptosis and skeletal muscle degeneration. Here, we demonstrate genetic ablation of the …