Virological suppression and clinical management in response to viremia in South African HIV treatment program: a multicenter cohort study

LE Hermans, S Carmona, M Nijhuis… - PLoS …, 2020 - journals.plos.org
Background Uptake of antiretroviral treatment (ART) is expanding rapidly in low-and middle-
income countries (LMIC). Monitoring of virological suppression is recommended at 6 months …

Effect of HIV-1 low-level viraemia during antiretroviral therapy on treatment outcomes in WHO-guided South African treatment programmes: a multicentre cohort study

LE Hermans, M Moorhouse, S Carmona… - The Lancet infectious …, 2018 - thelancet.com
Background Antiretroviral therapy (ART) that enables suppression of HIV replication has
been successfully rolled out at large scale to HIV-positive patients in low-income and middle …

Long‐term outcome of an HIV‐treatment programme in Rural Africa: Viral suppression despite early mortality

RE Barth, HA Tempelman, R Moraba… - AIDS research and …, 2011 - Wiley Online Library
Objective. To define the long‐term (2–4 years) clinical and virological outcome of an
antiretroviral treatment (ART) programme in rural South Africa. Methods. We performed a …

Clinical outcomes after first‐line HIV treatment failure in South Africa: the next cascade of care

CC Iwuji, M Shahmanesh, O Koole, K Herbst… - HIV …, 2020 - Wiley Online Library
Introduction There is limited literature on the appropriateness of viral load (VL) monitoring
and management of detectable VL in public health settings in rural South Africa. Methods …

Recording of HIV viral loads and viral suppression in South African patients receiving antiretroviral treatment: a multicentre cohort study

T Pillay, M Cornell, MP Fox, J Euvrard, G Fatti… - Antiviral …, 2020 - journals.sagepub.com
Background Viral suppression in patients on antiretroviral treatment (ART) is critical to
reducing HIV transmission and HIV-related mortality. Although many studies have evaluated …

Evaluation of WHO criteria for viral failure in patients on antiretroviral treatment in resource‐limited settings

B Castelnuovo, J Sempa, KN Agnes… - AIDS Research and …, 2011 - Wiley Online Library
Our objective was to evaluate outcomes in patients with sustained viral suppression
compared to those with episodes of viremia. Methods. In a prospective cohort of patients …

Factors associated with viral suppression and rebound among adult HIV patients on treatment: a retrospective study in Ghana

S Opoku, SA Sakyi, NK Ayisi-Boateng… - AIDS Research and …, 2022 - Springer
Background Viral suppression remains the most desired outcome in the management of
patients with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome …

How accurately do routinely reported HIV viral load suppression proportions reflect progress towards the 90-90-90 target in the population on antiretroviral treatment in …

J Euvrard, T Schulz, K Hilderbrand… - South African Medical …, 2019 - journals.co.za
Background. The Joint United Nations Programme on HIV/AIDS (UNAIDS) third 90-90-90
target requires 90% of patients on antiretroviral treatment (ART) to be virally suppressed (< 1 …

Virological follow-up of adult patients in antiretroviral treatment programmes in sub-Saharan Africa: a systematic review

RE Barth, MFS van der Loeff, R Schuurman… - The Lancet infectious …, 2010 - thelancet.com
Following large-scale roll-out of antiretroviral therapy in sub-Saharan Africa, the non-clinical
efficacy of antiretroviral therapy has received little attention. We aimed to systematically …

Low-level viraemia among people living with HIV in Nigeria: a retrospective longitudinal cohort study

HM Chun, A Abutu, K Milligan, A Ehoche… - The Lancet Global …, 2022 - thelancet.com
Background HIV transmission can occur with a viral load of at least 200 copies per mL of
blood and low-level viraemia can lead to virological failure; the threshold level at which risk …