AIP inactivation leads to pituitary tumorigenesis through defective Gαi-cAMP signaling
I Tuominen, E Heliövaara, A Raitila, MR Rautiainen… - Oncogene, 2015 - nature.com
The aryl hydrocarbon receptor interacting protein (AIP) is a tumor-suppressor gene
underlying the pituitary adenoma predisposition. Thus far, the exact molecular mechanisms …
underlying the pituitary adenoma predisposition. Thus far, the exact molecular mechanisms …
The expression of AIP-related molecules in elucidation of cellular pathways in pituitary adenomas
E Heliövaara, A Raitila, V Launonen, A Paetau… - The American journal of …, 2009 - Elsevier
Germline mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene
predispose to the development of pituitary adenomas. Here, we characterized AIP mutation …
predispose to the development of pituitary adenomas. Here, we characterized AIP mutation …
AIP mutations impair AhR signaling in pituitary adenoma patients fibroblasts and in GH3 cells
AL Lecoq, S Viengchareun, M Hage… - Endocrine-related …, 2016 - erc.bioscientifica.com
Germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene
predispose humans to pituitary adenomas through unknown molecular mechanisms. The …
predispose humans to pituitary adenomas through unknown molecular mechanisms. The …
[HTML][HTML] Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland
LC Hernández-Ramírez, RML Morgan, S Barry… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Despite the well-recognized role of loss-of-function mutations of the aryl hydrocarbon
receptor interacting protein gene (AIP) predisposing to pituitary adenomas, the pituitary …
receptor interacting protein gene (AIP) predisposing to pituitary adenomas, the pituitary …
The role of the aryl hydrocarbon receptor-interacting protein gene in familial and sporadic pituitary adenomas
CA Leontiou, M Gueorguiev… - The Journal of …, 2008 - academic.oup.com
Context: Mutations have been identified in the aryl hydrocarbon receptor-interacting protein
(AIP) gene in familial isolated pituitary adenomas (FIPA). It is not clear, however, how this …
(AIP) gene in familial isolated pituitary adenomas (FIPA). It is not clear, however, how this …
AIP and its interacting partners.
G Trivellin, M Korbonits - The Journal of endocrinology, 2011 - europepmc.org
Germline mutations in the aryl hydrocarbon receptor-interacting protein gene (AIP)
predispose to young-onset pituitary tumours, most often to GH-or prolactin-secreting …
predispose to young-onset pituitary tumours, most often to GH-or prolactin-secreting …
Familial Isolated Pituitary Adenomas (FIPA) and the Pituitary Adenoma Predisposition due to Mutations in the Aryl Hydrocarbon Receptor Interacting Protein (AIP) …
Pituitary adenomas are one of the most frequent intracranial tumors and occur with a
prevalence of approximately 1: 1000 in the developed world. Pituitary adenomas have a …
prevalence of approximately 1: 1000 in the developed world. Pituitary adenomas have a …
Screening for AIP gene mutations in a Han Chinese pituitary adenoma cohort followed by LOH analysis
F Cai, YD Zhang, X Zhao, YK Yang… - European journal of …, 2013 - academic.oup.com
Objective The aryl hydrocarbon receptor interacting protein gene (AIP) is associated with
pituitary adenoma (PA). AIP has not been sequenced in East Asian PA populations, so we …
pituitary adenoma (PA). AIP has not been sequenced in East Asian PA populations, so we …
Characterization of aryl hydrocarbon receptor interacting protein (AIP) mutations in familial isolated pituitary adenoma families
S Igreja, HS Chahal, P King, GB Bolger… - Human …, 2010 - Wiley Online Library
Familial isolated pituitary adenoma (FIPA) is an autosomal dominant condition with variable
genetic background and incomplete penetrance. Germline mutations of the aryl hydrocarbon …
genetic background and incomplete penetrance. Germline mutations of the aryl hydrocarbon …
[HTML][HTML] The Aryl Hydrocarbon Receptor Interacting Protein in cancer and immunity: Beyond a chaperone protein for the dioxin receptor
SA Kazzaz, J Tawil, EW Harhaj - Journal of Biological Chemistry, 2024 - Elsevier
The aryl hydrocarbon receptor (AhR) interacting protein (AIP) is a ubiquitously expressed,
immunophilin-like protein best known for its role as a co-chaperone in the AhR-AIP-Hsp90 …
immunophilin-like protein best known for its role as a co-chaperone in the AhR-AIP-Hsp90 …