[PDF][PDF] Investigating the Role of EZH2 and PRC2 in WT1/BASP1-mediated Gene Regulation
PE Crawley - 2022 - research-information.bris.ac.uk
Multiple mechanisms influence transcriptional control, with mounting evidence proving that
gene expression is directly correlated to the accessibility of the DNA sequence to RNA …
gene expression is directly correlated to the accessibility of the DNA sequence to RNA …
JARID2 and AEBP2 regulate PRC2 activity in the presence of H2A ubiquitination or other histone modifications
V Kasinath, C Beck, P Sauer, S Poepsel, J Kosmatka… - BioRxiv, 2020 - biorxiv.org
The Polycomb repressive complexes PRC1 and PRC2 functionally interact to coordinate cell
type identity by the epigenetic regulation of gene expression. It has been proposed that …
type identity by the epigenetic regulation of gene expression. It has been proposed that …
[图书][B] Deciphering the biochemical crosstalk of histone sumoylation in human chromatin
CJA Leonen - 2021 - search.proquest.com
The histone code hypothesis states that posttranslational modifications (PTMs) of amino
acids at the histone protein termini can combinatorially regulate key DNA processes such as …
acids at the histone protein termini can combinatorially regulate key DNA processes such as …
[HTML][HTML] Systems level analysis of histone H3 post-translational modifications (PTMs) reveals features of PTM crosstalk in chromatin regulation
Histones are abundant chromatin constituents carrying numerous post-translational
modifications (PTMs). Such PTMs mediate a variety of biological functions, including …
modifications (PTMs). Such PTMs mediate a variety of biological functions, including …
[HTML][HTML] Regulation of EZH2 by SMYD2-mediated lysine methylation is implicated in tumorigenesis
Y Zeng, R Qiu, Y Yang, T Gao, Y Zheng, W Huang… - Cell reports, 2019 - cell.com
The histone methyl transferase enhancer of zeste homolog 2 (EZH2) is a master
transcriptional regulator involved in histone H3 lysine 27 trimethylation. We aimed to …
transcriptional regulator involved in histone H3 lysine 27 trimethylation. We aimed to …
A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation
MAJ Morgan, RA Rickels, CK Collings… - Genes & …, 2017 - genesdev.cshlp.org
Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene cis-regulatory
sequences such as promoters and enhancers. Here we identify an evolutionarily conserved …
sequences such as promoters and enhancers. Here we identify an evolutionarily conserved …
[HTML][HTML] A monoclonal antibody raised against human EZH2 cross-reacts with the RNA-binding protein SAFB
RE Cherney, CA Mills, LE Herring… - Biology …, 2023 - journals.biologists.com
ABSTRACT The Polycomb Repressive Complex 2 (PRC2) is a conserved enzyme that tri-
methylates Lysine 27 on Histone 3 (H3K27me3) to promote gene silencing. PRC2 is …
methylates Lysine 27 on Histone 3 (H3K27me3) to promote gene silencing. PRC2 is …
Analyzing the In Vivo Roles of Histone Acetyltransferases GCN5 and ESA1 in RSC Recruitment and Remodeling Activity Genome-Wide in Saccharomyces cerevisiae
ER Biernat - 2023 - search.proquest.com
Transcription is important for gene expression and is a tightly-controlled process involving
multiple mechanisms of regulation, including regulation by chromatin structure. Chromatin …
multiple mechanisms of regulation, including regulation by chromatin structure. Chromatin …
[HTML][HTML] ARID1A-dependent maintenance of H3. 3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers
Abstract Background SWI/SNF (BAF) chromatin remodeling complexes regulate lineage-
specific enhancer activity by promoting accessibility for diverse DNA-binding factors and …
specific enhancer activity by promoting accessibility for diverse DNA-binding factors and …
[HTML][HTML] Role of EZH2 in cell lineage determination and relative signaling pathways
A Batool, C Jin, YX Liu - Frontiers in Bioscience-Landmark, 2019 - imrpress.com
Enhancer of zeste homolog 2 (EZH2), a catalytic component of polycomb repressive
complex 2 (PRC2), epigenetically regulates chromatin structure and gene expression …
complex 2 (PRC2), epigenetically regulates chromatin structure and gene expression …