Genome-wide association study of breast cancer in the Japanese population

SK Low, A Takahashi, K Ashikawa, J Inazawa, Y Miki… - PloS one, 2013 - journals.plos.org
Breast cancer is the most common malignancy among women in worldwide including
Japan. Several studies have identified common genetic variants to be associated with the …

Identification of two novel breast cancer loci through large-scale genome-wide association study in the Japanese population

SK Low, YM Chin, H Ito, K Matsuo, C Tanikawa… - Scientific Reports, 2019 - nature.com
Genome-wide association studies (GWAS) have successfully identified about 70 genomic
loci associated with breast cancer. Owing to the complexity of linkage disequilibrium and …

A genetic risk predictor for breast cancer using a combination of low-penetrance polymorphisms in a Japanese population

A Sueta, H Ito, T Kawase, K Hirose, S Hosono… - Breast cancer research …, 2012 - Springer
Genome-wide association studies (GWASs) have identified genetic variants associated with
breast cancer. Most GWASs to date have been conducted in women of European descent …

Genome-wide association study identifies breast cancer risk variant at 10q21. 2: results from the Asia Breast Cancer Consortium

Q Cai, J Long, W Lu, S Qu, W Wen… - Human molecular …, 2011 - academic.oup.com
Although approximately 20 common genetic susceptibility loci have been identified for
breast cancer risk through genome-wide association studies (GWASs), genetic risk variants …

Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women

W Zheng, W Wen, YT Gao, Y Shyr… - Journal of the …, 2010 - academic.oup.com
Background Most of the genetic variants identified from genome-wide association studies of
breast cancer have not been validated in Asian women. No risk assessment model that …

Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer

J Long, Q Cai, H Sung, J Shi, B Zhang, JY Choi… - PLoS …, 2012 - journals.plos.org
Genetic factors play an important role in the etiology of both sporadic and familial breast
cancer. We aimed to discover novel genetic susceptibility loci for breast cancer. We …

Evaluation of breast cancer susceptibility loci in Chinese women

J Long, XO Shu, Q Cai, YT Gao, Y Zheng, G Li… - … , biomarkers & prevention, 2010 - AACR
Background: Recent genome-wide association studies (GWAS), mostly conducted among
women of European ancestry, have identified 16 single-nucleotide polymorphisms (SNP) …

Associations of two common genetic variants with breast cancer risk in a Chinese population: a stratified interaction analysis

Y Lin, F Fu, M Chen, M Huang, C Wang - PloS one, 2014 - journals.plos.org
Recent genome-wide association studies (GWAS) have identified a series of new genetic
susceptibility loci for breast cancer (BC). However, the correlations between these variants …

Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controls

W Zheng, B Zhang, Q Cai, H Sung… - Human molecular …, 2013 - academic.oup.com
In a consortium including 23 637 breast cancer patients and 25 579 controls of East Asian
ancestry, we investigated 70 single-nucleotide polymorphisms (SNPs) in 67 independent …

Re-evaluating genetic variants identified in candidate gene studies of breast cancer risk using data from nearly 280,000 women of Asian and European ancestry

Y Yang, X Shu, X Shu, MK Bolla, SS Kweon, Q Cai… - …, 2019 - thelancet.com
Background We previously conducted a systematic field synopsis of 1059 breast cancer
candidate gene studies and investigated 279 genetic variants, 51 of which showed …