Psoriasis, characterized by aberrant epidermal keratinocyte proliferation and differentiation,
is a chronic inflammatory immune-related skin disease. Diosmetin (Dios), derived from citrus …

Diosmin is a flavonoid with promising anti-inflammatory and antioxidant properties.
However, it has difficult physicochemical characteristics since its solubility demands a pH …

Aims Psoriasis is a cutaneous disease mainly characterized by keratinocyte
hyperproliferation, abnormal epidermal differentiation, inflammation and angiogenesis. In …

Background: Psoriasis is a common skin inflammatory disease. Dysregulated growth and
differentiation of keratinocytes are the main characteristics of psoriasis. Diosmetin is a …

Psoriatic skin inflammation is mainly driven by complex interactions of infiltrating immune
cells and activated keratinocytes. Keratinocytes play an active role in initiating and …

Psoriasis is an incurable immune-mediated disease affecting the skin or the joints. There are
continuing studies on drugs for psoriasis prevention and treatment. This research found that …

Abstract The IL-17-producing CD4+ T cell and γδT cells play critical roles in the
pathogenesis of psoriasis (PS). PSORI-CM02 is a representative herbal formula for the …

Immune-mediated inflammation contributes to the development of psoriasis. However, long-
term treatment with global immunosuppressive agents may cause a variety of side effects …

Psoriasis is a common chronic inflammatory skin disease, which has seriously affected
human health. Berberine is a plant alkaloid with significant anti-inflammatory effect. In this …

Purpose Psoriasis is a skin disease characterized by excessive proliferation, inflammation
and oxidative stress in keratinocytes. The present study aimed to investigate the therapeutic …