Identification of potential early diagnostic biomarkers of sepsis

Z Li, B Huang, W Yi, F Wang, S Wei, H Yan… - Journal of …, 2021 - Taylor & Francis
Objective: The goal of this article was to identify potential biomarkers for early diagnosis of
sepsis in order to improve their survival. Methods: We analyzed differential gene expression …

Screening of key genes of sepsis and septic shock using bioinformatics analysis

X Zeng, J Feng, Y Yang, R Zhao, Q Yu… - Journal of …, 2021 - Taylor & Francis
Objective: Sepsis is a disease associated with high mortality. We performed bioinformatic
analysis to identify key biomarkers associated with sepsis and septic shock. Methods: The …

Identification of potential biomarkers and immune features of sepsis using bioinformatics analysis

FC Gong, R Ji, YM Wang, ZT Yang… - Mediators of …, 2020 - Wiley Online Library
Sepsis remains a major global concern and is associated with high mortality and morbidity
despite improvements in its management. Markers currently in use have shortcomings such …

Bioinformatics analysis of gene expression profiles for diagnosing sepsis and risk prediction in patients with sepsis

H Choi, JY Lee, H Yoo, K Jeon - International Journal of Molecular …, 2023 - mdpi.com
Although early recognition of sepsis is essential for timely treatment and can improve sepsis
outcomes, no marker has demonstrated sufficient discriminatory power to diagnose sepsis …

[HTML][HTML] Identification of a four-gene signature for diagnosing paediatric sepsis

Y Yao, J Zhao, J Hu, H Song, S Wang… - BioMed research …, 2022 - pmc.ncbi.nlm.nih.gov
Aim Early diagnosis of paediatric sepsis is crucial for the proper treatment of children and
reduction of hospitalization and mortality. Biomarkers are a convenient and effective method …

SDF4 Is a Prognostic Factor for 28-Days Mortality in Patients With Sepsis via Negatively Regulating ER Stress

T Zhu, Q Su, C Wang, L Shen, H Chen, S Feng… - Frontiers in …, 2021 - frontiersin.org
Sepsis is a heterogeneous syndrome induced by infection and results in high mortality. Even
though more than 100 biomarkers for sepsis prognosis were evaluated, prediction of patient …

Comprehensive analysis of molecular subtypes and hub genes of sepsis by gene expression profiles

Y Lai, C Lin, X Lin, L Wu, Y Zhao, T Shao, F Lin - Frontiers in Genetics, 2022 - frontiersin.org
Background: Sepsis is a systemic inflammatory response syndrome (SIRS) with
heterogeneity of clinical symptoms. Studies further exploring the molecular subtypes of …

Constructing a 10‐core genes panel for diagnosis of pediatric sepsis

X Zhou, Y Wang, J Chen, J Pan - Journal of Clinical Laboratory …, 2021 - Wiley Online Library
Background The lack of sensitivity and specificity of most biomarkers or the lack of relevant
studies to demonstrate their effectiveness in sepsis. Methods Downloaded three sets of …

Identifying potential effective diagnostic and prognostic biomarkers in sepsis by bioinformatics analysis and validation

X Huang, J Tan, X Chen, L Zhao - International Journal of General …, 2022 - Taylor & Francis
Purpose Sepsis is a serious life-threatening condition characterised by multi-organ failure
due to a disturbed immune response caused by severe infection. The pathogenesis of …

Identification of potential biomarkers of sepsis using bioinformatics analysis

YX Yang, L Li - Experimental and Therapeutic …, 2017 - spandidos-publications.com
Sepsis is defined as the systemic inflammatory response to infection and is one of the
leading causes of mortality in critically ill patients. The goal of the present study is to …