Combination nanotherapeutics for dry eye disease treatment in a rabbit model
L Huang, H Gao, Z Wang, Y Zhong… - International Journal of …, 2021 - Taylor & Francis
Purpose Anti-inflammation is essential for dry eye disease. Traditional anti-inflammation
agent corticosteroids applied in dry eye disease (DED) treatment could result in high …
agent corticosteroids applied in dry eye disease (DED) treatment could result in high …
[HTML][HTML] Comprehensive dry eye therapy: overcoming ocular surface barrier and combating inflammation, oxidation, and mitochondrial damage
Y Xia, Y Zhang, Y Du, Z Wang, L Cheng… - Journal of …, 2024 - Springer
Abstract Background Dry Eye Disease (DED) is a prevalent multifactorial ocular disease
characterized by a vicious cycle of inflammation, oxidative stress, and mitochondrial …
characterized by a vicious cycle of inflammation, oxidative stress, and mitochondrial …
Mucoadhesive liposomal delivery system synergizing anti-inflammation and anti-oxidation for enhanced treatment against dry eye disease
K Huang, R Guo, H Luo, H Liu, D Chen, T Deng… - Journal of Controlled …, 2024 - Elsevier
Dry eye disease (DED) is a common and frequent ocular surface disease worldwide, which
can cause severe ocular surface discomfort and blurred vision. Inflammation and reactive …
can cause severe ocular surface discomfort and blurred vision. Inflammation and reactive …
Anti-oxidative and mucin-compensating dual-functional nano eye drops for synergistic treatment of dry eye disease
K Jin, Y Ge, Z Ye, X Pan, Y Yan, Z Mao, J Ye - Applied Materials Today, 2022 - Elsevier
Oxidative stress plays a central role in dry eye disease (DED), which can destroy the mucin
layer on the ocular surface. The currently available eye drops are palliative and short-lived …
layer on the ocular surface. The currently available eye drops are palliative and short-lived …
A topical fluorometholone nanoformulation fabricated under aqueous condition for the treatment of dry eye
T Wang, B Guan, X Liu, L Ke, J Wang, K Nan - Colloids and Surfaces B …, 2022 - Elsevier
Fluorometholone (FMT) is a frequently prescribed drug for the alleviation of dry eye.
However, due to low aqueous solubility, it has been routinely used as an ophthalmic …
However, due to low aqueous solubility, it has been routinely used as an ophthalmic …
[HTML][HTML] Tacrolimus loaded cationic liposomes for dry eye treatment
X Chen, J Wu, X Lin, X Wu, X Yu, B Wang… - Frontiers in …, 2022 - frontiersin.org
Eye drops are ophthalmic formulations routinely used to treat dry eye. However, the low
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …
ocular bioavailability is an obvious drawback of eye drops owing to short ocular retention …
Therapeutic effect and mechanism of action of pterostilbene nano drugs in dry eye models
K Li, M Lin, K Huang, J Han, L Wei, L Miao… - Experimental Eye …, 2024 - Elsevier
Dry eye disease is a multifactorial dysfunction of the tear film and ocular surface, with
etiology involving inflammation and oxidative stress on the ocular surface. Pterostilbene …
etiology involving inflammation and oxidative stress on the ocular surface. Pterostilbene …
[HTML][HTML] Recent progress of nanomedicine in managing dry eye disease
Z Lv, S Li, G Zeng, K Yao, H Han - Advances in Ophthalmology Practice and …, 2024 - Elsevier
Background Dry eye disease (DED) is a commonly reported ocular complaint that has
garnered significant attention in recent research. The global occurrence of DED ranges from …
garnered significant attention in recent research. The global occurrence of DED ranges from …
[HTML][HTML] Dexamethasone-loaded nanostructured lipid carriers for the treatment of dry eye disease
Dry eye disease (DED) or keratoconjunctivitis sicca is a chronic multifactorial disorder of the
ocular surface caused by tear film dysfunction. Symptoms include dryness, irritation …
ocular surface caused by tear film dysfunction. Symptoms include dryness, irritation …
[HTML][HTML] Recent Advances in Nanotechnology for the Treatment of Dry Eye Disease
G Coco, G Buffon, A Taloni, G Giannaccare - Nanomaterials, 2024 - mdpi.com
Dry eye disease (DED) incidence is continuously growing, positioning it to become an
emergent health issue over the next few years. Several topical treatments are commonly …
emergent health issue over the next few years. Several topical treatments are commonly …