Recent advance of nanoparticle-based topical drug delivery to the posterior segment of the eye
Y Wang, X Xu, Y Gu, Y Cheng, F Cao - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Considering that the number of patients afflicted by posterior eye diseases is
increasing, effective drug delivery is currently in high clinical demand. Topical administration …
increasing, effective drug delivery is currently in high clinical demand. Topical administration …
A review of nanocarrier-mediated drug delivery systems for posterior segment eye disease: Challenges analysis and recent advances
R Wang, Y Gao, A Liu, G Zhai - Journal of drug targeting, 2021 - Taylor & Francis
Posterior segment eye disease is a leading cause of irreversible vision impairment and
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
blindness. As the unique organ for vision, eyes are protected by various protective barriers …
Nanoparticles for drug delivery to the anterior segment of the eye
Commercially available ocular drug delivery systems are effective but less efficacious to
manage diseases/disorders of the anterior segment of the eye. Recent advances in …
manage diseases/disorders of the anterior segment of the eye. Recent advances in …
Nanotherapy for posterior eye diseases
IP Kaur, S Kakkar - Journal of Controlled Release, 2014 - Elsevier
It is assumed that more than 50% of the most enfeebling ocular diseases have their origin in
the posterior segment. Furthermore, most of these diseases lead to partial or complete …
the posterior segment. Furthermore, most of these diseases lead to partial or complete …
Recent advances in topical nano drug-delivery systems for the anterior ocular segment
Over the past decade, there has been a rise in the number of clinical cases of moderate to
severe anterior segment ocular diseases. Conventional topical ophthalmic formulations …
severe anterior segment ocular diseases. Conventional topical ophthalmic formulations …
When nanotechnology meets the ocular surface
Controlled and sustained delivery of drugs for ophthalmic diseases continues to remain a
major challenge in the field of pharmaceutical drug delivery. To overcome the problems of …
major challenge in the field of pharmaceutical drug delivery. To overcome the problems of …
[HTML][HTML] Lipid-based nanocarriers as topical drug delivery systems for intraocular diseases
J Navarro-Partida, CR Castro-Castaneda… - Pharmaceutics, 2021 - mdpi.com
Effective drug delivery to intraocular tissues remains a great challenge due to complex
anatomical and physiological barriers that selectively limit the entry of drugs into the eye. To …
anatomical and physiological barriers that selectively limit the entry of drugs into the eye. To …
Trends in formulation approaches for sustained drug delivery to the posterior segment of the eye
The eye, an intricate organ comprising physical and physiological barriers, poses a
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …
significant challenge for ophthalmic physicians seeking to treat serious ocular diseases …
Drug delivery systems to the posterior segment of the eye: implants and nanoparticles
Intraocular diseases in some cases lead to surgical treatment of posterior segments of the
eye. In addition, lack of effective treatment culminates in partial or complete blindness in …
eye. In addition, lack of effective treatment culminates in partial or complete blindness in …
[HTML][HTML] Ocular drug delivery barriers—role of nanocarriers in the treatment of anterior segment ocular diseases
Ocular drug delivery is challenging due to the presence of anatomical and physiological
barriers. These barriers can affect drug entry into the eye following multiple routes of …
barriers. These barriers can affect drug entry into the eye following multiple routes of …