Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Drug bioavailability is a crucial aspect of pharmacology, affecting the effectiveness of drug
therapy. Understanding how drugs are absorbed, distributed, metabolized, and eliminated in …

Optimisation of oral bioavailability is a continuing challenge for the pharmaceutical and
biotechnology industries. The number of potential drug candidates requiring invivo …

The importance of adequate and validated analytical methodology used in biostudies for
interpretation of pharmacokinetic data is discussed. The performance characteristics of …

Drug'developability'assessment has become an increasingly important addition to traditional
drug efficacy and toxicity evaluations, as pharmaceutical scientists strive to accelerate drug …

Oral bioavailability is a key consideration in development of drug products, and the use of
preclinical species in predicting bioavailability in human has long been debated. In order to …

In recent years drug bioavailability has become a subject of interest not only in drug
development, but also in the early stages of drug discovery. This is a consequence of the …

Drug absorption, sufficient and reproducible bioavailability and/or pharmacokinetic profile in
humans are recognized today as one of the major challenges in oral delivery of new drug …

" Provides a comprehensive summary of the continuously growing literature and research
activities on the regulatory requirements, scientific and practical issues, and statistical …

Measurement of drug concentrations in biological matrices (such as serum, plasma, faces,
skin, blood, urine, saliva and other organ tissues) is an important aspect of medicinal …