Transductomics: sequencing-based detection and analysis of transduced DNA in pure cultures and microbial communities

M Kleiner, B Bushnell, KE Sanderson, LV Hooper… - Microbiome, 2020 - Springer
Background Horizontal gene transfer (HGT) plays a central role in microbial evolution. Our
understanding of the mechanisms, frequency, and taxonomic range of HGT in polymicrobial …

Examining horizontal gene transfer in microbial communities

IL Brito - Nature Reviews Microbiology, 2021 - nature.com
Bacteria acquire novel DNA through horizontal gene transfer (HGT), a process that enables
an organism to rapidly adapt to changing environmental conditions, provides a competitive …

Current and promising approaches to identify horizontal gene transfer events in metagenomes

GM Douglas, MGI Langille - Genome biology and evolution, 2019 - academic.oup.com
High-throughput shotgun metagenomics sequencing has enabled the profiling of myriad
natural communities. These data are commonly used to identify gene families and pathways …

Identical sequences found in distant genomes reveal frequent horizontal transfer across the bacterial domain

M Sheinman, K Arkhipova, PF Arndt, BE Dutilh… - Elife, 2021 - elifesciences.org
Horizontal gene transfer (HGT) is an essential force in microbial evolution. Despite detailed
studies on a variety of systems, a global picture of HGT in the microbial world is still missing …

Dynamics of bacterial recombination in the human gut microbiome

Z Liu, BH Good - Plos Biology, 2024 - journals.plos.org
Horizontal gene transfer (HGT) is a ubiquitous force in microbial evolution. Previous work
has shown that the human gut is a hotspot for gene transfer between species, but the more …

Are all horizontal gene transfers created equal? Prospects for mechanism-based studies of HGT patterns

JR Zaneveld, DR Nemergut, R Knight - Microbiology, 2008 - microbiologyresearch.org
Detecting patterns of horizontal gene transfer (HGT) in genomic sequences is an important
problem, with implications for evolution, ecology, biotechnology and medicine. Extensive …

Horizontal gene transfer: perspectives at a crossroads of scientific disciplines.

BF Smets, T Barkay - Nature Reviews Microbiology, 2005 - nature.com
Horizontal gene transfer (HGT) has a crucial role in microbial evolution, in shaping the
structure and function of microbial communities and in controlling a myriad of environmental …

Quantitative analysis of horizontal gene transfer in complex systems

J Moralez, K Szenkiel, K Hamilton, A Pruden… - Current Opinion in …, 2021 - Elsevier
Highlights•Microbial HGT is a complex process influenced by a variety of modulating factors,
including cellular genetics and environmental conditions.•HGT dynamics are governed by …

Horizontal gene flow in microbial communities

T Barkay, BF Smets - Asm News, 2005 - osti.gov
Genetic exchanges among prokaryotes, formerly considered only a marginal phenomenon,
increasingly are being viewed as profoundly affecting evolution. Indeed, some researchers …

Horizontal gene transfer and adaptive evolution in bacteria

BJ Arnold, IT Huang, WP Hanage - Nature Reviews Microbiology, 2022 - nature.com
Horizontal gene transfer (HGT) is arguably the most conspicuous feature of bacterial
evolution. Evidence for HGT is found in most bacterial genomes. Although HGT can …