Cancers harbor significant genetic heterogeneity and patterns of relapse following many
therapies are due to evolved resistance to treatment. While efforts have been made to …

The immune system has crucial roles in cancer development and treatment. Whereas
adaptive immunity can prevent or constrain cancer through immunosurveillance, innate …

Inflammation has accompanied human beings since the emergence of wounds and
infections. In the past decades, numerous efforts have been undertaken to explore the …

Chronic infections, obesity, alcohol, tobacco, radiation, environmental pollutants, and high-
calorie diet have been recognized as major risk factors for the most common types of cancer …

Inflammatory cells and mediators are an essential component of the tumor
microenvironment. Inflammatory circuits can differ considerably in different tumors in terms of …

Epidemiological and experimental evidence has emerged that a dysregulated inflammation
is associated with most of the tumors. Recent studies have begun to unravel molecular …

An inflammatory component is present in the microenvironment of most neoplastic tissues,
including those not causally related to an obvious inflammatory process. Epidemiological …

There are clear links between chronic inflammation and cancer; strong epidemiological and
genetic evidence indicates that inflammation can drive tumour progression, and more-recent …

Over the last decade there has been significant progress towards the development of
personalized or “precision” medicine for many patients with cancer. However, there still …

F or the last 10 years, a dedicated cadre of researchers has been making a case for
inflammation as a major cause and promoter of cancer. They have succeeded, up to a point …