The anticholinergic, antimuscarinic compounds are potent and hitherto neglected
bronchodilators. Although atropine itself has drawbacks, principally related to its rapid …

Synopsis Ipratropium bromide 1 is an anticholinergic bronchodilator administered by
inhalation. Although producing bronchodilation in most patients with obstructive airways …

Ipratropium bromide (also known as Sch 1000) is a new atropine-like bronchodilator drug
whose mechanism of action is via an anticholinergic pathway and may decrease cyclic …

During the past 40 years a voluminous literature has accumulated on bronchodilator drugs
describing their basic pharmacology and their effects in patients with reversible airway …

Chronic obstructive pulmonary disease non-selective drugs such as ipratropium brom-
(COPD) is common, affecting 6% of men and ide and oxitropium bromide. M1 receptors ap …

The short-and long-term efficacy and safety of an inhaled quaternary ammonium
anticholinergic agent, ipratropium bromide, and a beta agonist aerosol, metaproterenol …

• Twenty-five subjects with moderate to severe chronic obstructive airway disease were
studied to compare the effect of ipratropium bromide, albuterol, and placebo on the forced …

Bronchial asthma is characterized by breathlessness and wheezing which are caused by
variable obstruction of the airways. The obstruction is reversible by appropriate treatment …

Twenty-one patients with severe chronic bronchitis and emphysema (FEV1 less than 1 1)
inhaled 80 microgram of the atropine-like agent ipratropium or placebo in a double-blind …

IPRATROPIUM bromide (8-isopropyl-noratropine-methobromide) is a synthetic quaternary
ammonium congener of atropine. The first anticholinergic agent to be approved for use as a …