Papillary thyroid cancer (PTC) is the main histological type of thyroid cancer and accounts
for almost all increased cases worldwide. Patients with PTC exhibit a favorable prognosis …

Abstract Background Inhibitor of DNA Binding 2 (ID2) plays a crucial role in tumor cell
proliferation, invasion, metastasis, and stemness. Aberrant ID2 expression is associated with …

Papillary thyroid cancer (PTC) is the most common thyroid malignancy. Although PTC
usually has a favorable prognosis, some aggressive PTC subtypes and lymph node (LN) …

Background Anaplastic thyroid carcinoma (ATC), a rare but highly aggressive endocrine
malignancy, is characterized by a significant presence of cancer stem-like cells (CSCs) …

Characterisation of molecular mechanisms that control tumour invasion is a crucial step for
the identification of molecular markers to apply in cancer diagnosis and treatment. In this …

Lymph node metastasis (LNM) is a major cause of locoregional recurrence of papillary
thyroid carcinoma (PTC). However, the mechanisms responsible for LNM are unclear …

Abstract Papillary Thyroid Cancer (PTC) is the most common type of thyroid cancer. The
membrane-associated glycoprotein cadherin-16 (CDH16) plays a significant role in the …

Background: Papillary thyroid cancers (PTCs) are common, usually indolent malignancies.
Still, a small but significant percentage of patients have aggressive tumors and develop …

ID genes have an important function in the cell cycle, and ID proteins may help identify
aggressive tumors, besides being considered promising therapeutic targets. However, their …

Background: As an actin cytoskeleton interactor, PDZ (postsynaptic density 65-discs large-
zonula occludens 1) and LIM (abnormal cell lineage 11-isket 1-mechanosensory abnormal …