A smart nanoassembly for multistage targeted drug delivery and magnetic resonance imaging

Z Li, K Dong, S Huang, E Ju, Z Liu… - Advanced Functional …, 2014 - Wiley Online Library
Efficient delivery of DNA‐toxin anticancer drugs into nucleus of targeted tumor cells while
simultaneously minimizing the side effects to normal tissue is a major challenge for cancer …

Rational design of multifunctional magnetic mesoporous silica nanoparticle for tumor-targeted magnetic resonance imaging and precise therapy

WH Chen, GF Luo, Q Lei, FY Cao, JX Fan, WX Qiu… - Biomaterials, 2016 - Elsevier
In this paper, a multifunctional theranostic magnetic mesoporous silica nanoparticle (MMSN)
with magnetic core was developed for magnetic-enhanced tumor-targeted MR imaging and …

Smart multifunctional nanostructure for targeted cancer chemotherapy and magnetic resonance imaging

T Chen, MI Shukoor, R Wang, Z Zhao, Q Yuan… - ACS …, 2011 - ACS Publications
Targeted chemotherapy and magnetic resonance imaging of cancer cells in vitro has been
achieved using a smart multifunctional nanostructure (SMN) constructed from a porous …

A magnetic drug delivery system with “OFF–ON” state via specific molecular recognition and conformational changes for precise tumor therapy

J Liu, W Liu, K Zhang, J Shi… - Advanced Healthcare …, 2020 - Wiley Online Library
To enhance the tumor‐targeting and tumor cell‐specific drug‐release capacity of nano drug
delivery systems, a magnetic resonance imaging‐traceable, magnetic‐targeted …

Cancer therapeutic proficiency of dual-targeted mesoporous silica nanocomposite endorses combination drug delivery

C Murugan, S Venkatesan, S Kannan - ACS omega, 2017 - ACS Publications
The cargo-loaded mesoporous silica nanoparticles (MSNs) with convenient surface
modification can facilitate the development of the innovative nanodrug system. Herein, the …

A dual‐responsive mesoporous silica nanoparticle for tumor‐triggered targeting drug delivery

D Xiao, HZ Jia, J Zhang, CW Liu, RX Zhuo, XZ Zhang - Small, 2014 - Wiley Online Library
A novel pH‐and redox‐dual‐responsive tumor‐triggered targeting mesoporous silica
nanoparticle (TTTMSN) is designed as a drug carrier. The peptide RGDFFFFC is anchored …

Smart “on-off” responsive drug delivery nanosystems for potential imaging diagnosis and targeted tumor therapy

F Liu, P Huang, D Huang, S Liu, Q Cao, X Dong… - Chemical Engineering …, 2019 - Elsevier
Cancer is one of the most concerned diseases in the world, where there is still no reported
specifically targeted drugs with high effect. In this study, mesoporous silica with a large pore …

MMP-responsive theranostic nanoplatform based on mesoporous silica nanoparticles for tumor imaging and targeted drug delivery

JJ Hu, LH Liu, ZY Li, RX Zhuo, XZ Zhang - Journal of Materials …, 2016 - pubs.rsc.org
In this paper, we report on an intelligent mesoporous silica-based multifunctional theranostic
nanoplatform (designated as MMTNP) for tumor imaging as well as controlled drug release …

Inorganic nanocarriers overcoming multidrug resistance for cancer theranostics

G Lin, P Mi, C Chu, J Zhang, G Liu - Advanced science, 2016 - Wiley Online Library
Cancer multidrug resistance (MDR) could lead to therapeutic failure of chemotherapy and
radiotherapy, and has become one of the main obstacles to successful cancer treatment …

A smart magnetic nanosystem with controllable drug release and hyperthermia for potential cancer therapy

Y Xu, Y Zhu, S Kaskel - RSC advances, 2015 - pubs.rsc.org
We have successfully constructed a smart therapeutic platform with potential controllable
drug release and magnetic hyperthermia through the conjugation of carboxyl-modified …