Erythropoiesis, the development of erythrocytes from hematopoietic stem cells, occurs
through four phases: erythroid progenitor (EP) development, early erythropoiesis, terminal …

Erythroid cells, the most prevalent cell type in blood, are one of the earliest products and
permeate through the entire process of hematopoietic development in the human body, the …

Fine-resolution differentiation trajectories of adult human hematopoietic stem cells (HSCs)
involved in the generation of red cells is critical for understanding dynamic developmental …

The processes of differentiation and maturation that lead to the formation of functional red
cells presumably require an orderly sequence of events that influence different stages of the …

The various cellular elements of blood-lymphoid, cry throid, myeloid and megakatyocytic-all
originate from a self-renewing population of multipotential haemopoetic stem cells, originally …

The major myeloid blood cell lineages are generated from hematopoietic stem cells by
differentiation through a series of increasingly committed progenitor cells. Precise …

Through their oxygen delivery function, red blood cells are pivotal to the healthy existence of
all vertebrate organisms. These cells are required during all stages of life—embryonic, fetal …

Studies of human erythropoiesis have relied, for the most part, on the in vitro differentiation
of hematopoietic stem and progenitor cells (HSPC) from different sources. Here, we report …

To globally survey the changes in transcriptional landscape during terminal erythroid
differentiation, we performed RNA sequencing (RNA-seq) on primary human CD34+ cells …

Red blood cells (RBC s) are generated from haematopoietic stem and progenitor cells
(HSPC s) through the step‐wise process of differentiation known as erythropoiesis. In this …