Rheumatoid arthritis (RA) is a systemic inflammatory disease that causes chronic
inflammation of the joints. Analysis of genetic variants offers promise for guiding treatment …

Objective To investigate the mRNA and protein expression of high mobility group box
chromosomal protein 1 (HMGB1) in peripheral blood mononuclear cells (PBMCs) and …

High mobility group box 1 (HMGB1) chromosomal protein, an endogenous molecule with
multiple intra-and extracellular effects, is also defined as a novel proinflammatory cytokine …

Objective. To compare the expression of high mobility group box chromosomal protein 1
(HMGB1) and the modulating effects on its downstream cytokines in patients with systemic …

High mobility group box chromosomal protein 1 (HMGB1) is a ubiquitous highly conserved
single polypeptide in all mammal eukaryotic cells. HMGB1 exists mainly within the nucleus …

Objectives High mobility group box 1 protein (HMGB1) is an important late inflammatory
mediator in the body. In recent years, studies have found that it plays an important …

Objective. High mobility group box chromosomal protein 1 (HMGB1) has been implicated as
a mediator of inflammation in rheumatoid arthritis (RA), while its role in juvenile idiopathic …

High-mobility group box 1 (HMGB1) is associated with the development of rheumatoid
arthritis (RA). Recent studies have shown that methotrexate (MTX) may inhibit the …

High‐mobility group box 1 protein (HMGB1) is a nuclear DNA‐binding protein, which also
functions as a pleiotropic cytokine, implicated in the pathology of several different immune …

Rheumatoid arthritis (RA) remains a prevalent disease worldwide that causes significant
morbidity and mortality despite recent therapeutics. High mobility group box-1 (HMGB1) …