Transplantation of mesenchymal stem cells within a poly(lactide‐co‐ɛ‐caprolactone) scaffold improves cardiac function in a rat myocardial infarction model

J Jin, SI Jeong, YM Shin, KS Lim… - European journal of …, 2009 - Wiley Online Library
Aims Cardiac tissue engineering has been proposed as an appropriate method to repair
myocardial infarction (MI). Evidence suggests that a cell with scaffold combination was more …

Effects of cardiac patches engineered with bone marrow-derived mononuclear cells and PGCL scaffolds in a rat myocardial infarction model

H Piao, JS Kwon, S Piao, JH Sohn, YS Lee, JW Bae… - Biomaterials, 2007 - Elsevier
Little is known about the cardioprotective effects against heart failure (HF), the effects on
differentiation of bone marrow-derived mononuclear cell (BMMNC), and the biocompatibility …

The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat

J Yu, KT Du, Q Fang, Y Gu, SS Mihardja, RE Sievers… - Biomaterials, 2010 - Elsevier
The combination of scaffold material and cell transplantation therapy has been extensively
investigated in cardiac tissue engineering. However, many polymers are difficult to …

Mesenchymal stem cell delivery into rat infarcted myocardium using a porous polysaccharide-based scaffold: a quantitative comparison with endocardial injection

C Le Visage, O Gournay, N Benguirat… - … Engineering Part A, 2012 - liebertpub.com
The use of mesenchymal stem cells (MSCs) for tissue regeneration is often hampered by
modest engraftment in host tissue. This study was designed to quantitatively compare MSCs …

Bioengineered cardiac patch constructed from multilayered mesenchymal stem cells for myocardial repair

HJ Wei, CH Chen, WY Lee, I Chiu, SM Hwang, WW Lin… - Biomaterials, 2008 - Elsevier
Growing three-dimensional scaffolds that contain more than a few layers of seeded cells is
crucial for the creation of thick and viable cardiac tissues. To achieve this goal, a …

Plasma-functionalized electrospun matrix for biograft development and cardiac function stabilization

AG Guex, A Frobert, J Valentin, G Fortunato… - Acta biomaterialia, 2014 - Elsevier
Cardiac tissue engineering approaches can deliver large numbers of cells to the damaged
myocardium and have thus increasingly been considered as a possible curative treatment to …

Collagen matrices enhance survival of transplanted cardiomyoblasts and contribute to functional improvement of ischemic rat hearts

I Kutschka, IY Chen, T Kofidis, T Arai… - Circulation, 2006 - Am Heart Assoc
Background—Cardiac cell transplantation is limited by poor graft viability. We aimed to
enhance the survival of transplanted cardiomyoblasts using growth factor-supplemented …

Stem cell-loaded nanofibrous patch promotes the regeneration of infarcted myocardium with functional improvement in rat model

D Kai, QL Wang, HJ Wang, MP Prabhakaran, Y Zhang… - Acta biomaterialia, 2014 - Elsevier
Myocardial infarction (MI) leads to the loss of cardiomyocytes, followed by left ventricular
(LV) remodeling and cardiac dysfunction. The authors hypothesize that an elastic …

Collagen–GAG scaffolds grafted onto myocardial infarcts in a rat model: a delivery vehicle for mesenchymal stem cells

Z Xiang, R Liao, MS Kelly, M Spector - Tissue engineering, 2006 - liebertpub.com
Various cell delivery methods have been investigated for cell transplantation treatment of
cardiac infarcts. In this study, we investigated a type I collagen–glycosaminoglycan (GAG) …

Cardiac repair achieved by bone marrow mesenchymal stem cells/silk fibroin/hyaluronic acid patches in a rat of myocardial infarction model

NH Chi, MC Yang, TW Chung, JY Chen, NK Chou… - Biomaterials, 2012 - Elsevier
Bone marrow mesenchymal stem cells/silk fibroin/hyaluronic acid (BMSC/SH) patches were
implanted into myocardial infarction (MI) rat hearts to investigate the efficacies of them on …