Interim results of a phase 1–2a trial of Ad26. COV2. S Covid-19 vaccine

J Sadoff, M Le Gars, G Shukarev… - … England Journal of …, 2021 - Mass Medical Soc
Background Efficacious vaccines are urgently needed to contain the ongoing coronavirus
disease 2019 (Covid-19) pandemic of infection with severe acute respiratory syndrome …

Safety and efficacy of single-dose Ad26. COV2. S vaccine against Covid-19

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2021 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine is a recombinant, replication-incompetent
human adenovirus type 26 vector encoding full-length severe acute respiratory syndrome …

Safety and immunogenicity of the Ad26. COV2. S COVID-19 vaccine candidate: interim results of a phase 1/2a, double-blind, randomized, placebo-controlled trial

J Sadoff, ML Gars, G Shukarev, D Heerwegh, C Truyers… - MedRxiv, 2020 - medrxiv.org
ABSTRACT BACKGROUND The ongoing coronavirus disease (COVID)-19 pandemic
caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) might be …

Immunogenicity of the Ad26. COV2. S Vaccine for COVID-19

KE Stephenson, M Le Gars, J Sadoff, AM de Groot… - Jama, 2021 - jamanetwork.com
Importance Control of the global COVID-19 pandemic will require the development and
deployment of safe and effective vaccines. Objective To evaluate the immunogenicity of the …

Final analysis of efficacy and safety of single-dose Ad26. COV2. S

J Sadoff, G Gray, A Vandebosch… - … England Journal of …, 2022 - Mass Medical Soc
Abstract Background The Ad26. COV2. S vaccine was highly effective against severe–
critical coronavirus disease 2019 (Covid-19), hospitalization, and death in the primary phase …

[HTML][HTML] Efficacy, safety, and immunogenicity of a booster regimen of Ad26. COV2. S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind …

K Hardt, A Vandebosch, J Sadoff, M Le Gars… - The Lancet Infectious …, 2022 - thelancet.com
Background Despite the availability of effective vaccines against COVID-19, booster
vaccinations are needed to maintain vaccine-induced protection against variant strains and …

Safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 vectored COVID-19 vaccine: a dose-escalation, open-label, non-randomised, first-in …

FC Zhu, YH Li, XH Guan, LH Hou, WJ Wang, JX Li… - The Lancet, 2020 - thelancet.com
Background A vaccine to protect against COVID-19 is urgently needed. We aimed to assess
the safety, tolerability, and immunogenicity of a recombinant adenovirus type-5 (Ad5) …

Analysis of the effectiveness of the Ad26. COV2. S adenoviral vector vaccine for preventing COVID-19

J Corchado-Garcia, D Zemmour, T Hughes… - JAMA network …, 2021 - jamanetwork.com
Importance Continuous assessment of the effectiveness and safety of the US Food and Drug
Administration–authorized SARS-CoV-2 vaccines is critical to amplify transparency, build …

[HTML][HTML] Final efficacy analysis, interim safety analysis, and immunogenicity of a single dose of recombinant novel coronavirus vaccine (adenovirus type 5 vector) in …

SA Halperin, L Ye, D MacKinnon-Cameron, B Smith… - The Lancet, 2022 - thelancet.com
Summary Background The Ad5-nCoV vaccine is a single-dose adenovirus type 5 (Ad5)
vectored vaccine expressing the SARS-CoV-2 spike protein that was well-tolerated and …

[HTML][HTML] Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo …

Y Zhang, G Zeng, H Pan, C Li, Y Hu, K Chu… - The Lancet infectious …, 2021 - thelancet.com
Background With the unprecedented morbidity and mortality associated with the COVID-19
pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac …