Prevention of postoperative cognitive dysfunction by minocycline in elderly patients after total knee arthroplasty: a randomized, double-blind, placebo-controlled …
T Takazawa, T Horiuchi, M Orihara, K Nagumo… - …, 2023 - pubs.asahq.org
Background There are no effective pharmacologic interventions for preventing postoperative
cognitive dysfunction in daily practice. Since the antibiotic minocycline is known to suppress …
cognitive dysfunction in daily practice. Since the antibiotic minocycline is known to suppress …
Minocycline may be useful to prevent/treat postoperative cognitive decline in elderly patients
L Fan, TL Wang, YC Xu, YH Ma, WG Ye - Medical hypotheses, 2011 - Elsevier
Postoperative cognitive dysfunction (POCD) is reported to occur frequently after all types
especially cardiac surgery in elderly patients. It can be short-term or long-term and some …
especially cardiac surgery in elderly patients. It can be short-term or long-term and some …
High doses of minocycline may induce delayed activation of microglia in aged rats and thus cannot prevent postoperative cognitive dysfunction
W Li, Q Chai, H Zhang, J Ma, C Xu… - Journal of …, 2018 - journals.sagepub.com
Objective Postoperative cognitive dysfunction (POCD) is common after surgery in elderly
patients and is associated with high morbidity. The molecular mechanisms responsible for …
patients and is associated with high morbidity. The molecular mechanisms responsible for …
[PDF][PDF] Protective effect of combined general and regional anesthesia on postoperative cognitive function in older arthroplasty patients
C Chen, M Li, K Wang, J Shen, L Yang, X Bu… - Int J Clin Exp Med, 2017 - e-century.us
Purpose: Postoperative cognitive dysfunction (POCD) occurs frequently in elderly people
especially for those after major surgeries. Arthroplasty improves quality of life in elderly …
especially for those after major surgeries. Arthroplasty improves quality of life in elderly …
The prevalence of cognitive dysfunction after conventional and computer-assisted total knee replacement
H Deo, G West, C Butcher, P Lewis - The Knee, 2011 - Elsevier
Post operative cognitive dysfunction (POCD) is common following lower limb arthroplasty.
The prevalence varies from 41–75% at 7days to 18–45% at 3months post operatively. The …
The prevalence varies from 41–75% at 7days to 18–45% at 3months post operatively. The …
Preoperative cognitive impairment as a perioperative risk factor in patients undergoing total knee arthroplasty
S Krishnan, EY Brovman… - … Orthopaedic Surgery & …, 2021 - journals.sagepub.com
Background: The study assessed whether pre-existing cognitive impairment (CI) prior to
elective total knee arthroplasty (TKA) is associated with worse postoperative outcomes such …
elective total knee arthroplasty (TKA) is associated with worse postoperative outcomes such …
Postoperative cognitive changes after total knee arthroplasty under regional anesthesia
Background: The type of postoperative cognitive decline after surgery under spinal
anesthesia is unknown. We investigated the type of postoperative cognitive decline after …
anesthesia is unknown. We investigated the type of postoperative cognitive decline after …
Dose-dependent effects of intravenous methoxamine infusion during hip-joint replacement surgery on postoperative cognitive dysfunction and blood TNF-α level in …
S Sun, D Sun, L Yang, J Han, R Liu, L Wang - Bmc Anesthesiology, 2017 - Springer
Background Postoperative cognitive dysfunction (POCD), common in elderly patients, is
thought to be closely associated with intraoperative instability of hemodynamics and …
thought to be closely associated with intraoperative instability of hemodynamics and …
Effects of anesthetic adjunctive agents on postoperative cognitive dysfunction in elderly patients undergoing noncardiac surgery: A Bayesian network meta‐analysis
L Xu, S Xu, Y Zhang, Y Huang - Brain and Behavior, 2023 - Wiley Online Library
Background Elderly patients are prone to postoperative cognitive dysfunction (POCD). The
comparison of the effects of anesthetic adjuvant drugs on POCD in elderly patients …
comparison of the effects of anesthetic adjuvant drugs on POCD in elderly patients …
Perioperative use of erythromycin reduces cognitive decline after coronary artery bypass grafting surgery: a pilot study
E Thomaidou, H Argiriadou, G Vretzakis… - Clinical …, 2017 - journals.lww.com
Objectives Adverse neurologic outcome can be a debilitating complication after cardiac
surgery. The aim of this study was to investigate the potential neuroprotective action of …
surgery. The aim of this study was to investigate the potential neuroprotective action of …
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