Background/Aims Mesenchymal stem cells (MSCs) are potential alternatives for liver fibrosis
treatment; however, their optimal sources remain uncertain. This study compares the ex-vivo …

Introduction Liver fibrosis is characterized by excessive accumulation of extracellular matrix.
In a mouse model of liver fibrosis, systemic injection of bone marrow mesenchymal stem …

AIM To investigate the hepatic differentiation potential of human umbilical cord-derived
mesenchymal stem cells (hUC-MSCs) and to evaluate their therapeutic effect on liver …

Liver fibrosis is a wound-healing response to chronic injuries, characterized by the
excessive accumulation of extracellular matrix or scar tissue within the liver; in addition, its …

Background: The application of mesenchymal stem cell (MSC) therapy in liver fibrosis
treatment has been increasingly investigated in recent years. MSCs obtained from a variety …

Abstract Background Mesenchymal stem cells (MSCs) are multipotent stromal cells and
could exert hepatoprotective effects against acute liver injury, steatohepatitis, and …

Abstract Background/Aims: Although mesenchymal stem cells (MSCs) provide effective
therapy for liver fibrosis, there are conflicting data regarding their marginal therapeutic …

End-stage liver disease is a worldwide cause of morbidity and mortality, which is associated
with a considerable economic burden. As the disease progresses, fibrosis will replace the …

Background To investigate the heterogeneities of human umbilical cord mesenchymal
stromal cells (HUCMSCs) derived from different donors and their therapeutic variations …

Background Liver cirrhosis, a prevalent chronic liver disease, is characterized by liver
fibrosis as its central pathological process. Recent advancements highlight the clinical …