Remote ischemic per-conditioning: a novel therapy for acute stroke?
Background and Purpose—Remote ischemic preconditioning is a phenomenon by which a
short period of sublethal ischemia to an organ protects against subsequent ischemia in …
short period of sublethal ischemia to an organ protects against subsequent ischemia in …
A multicenter, randomized trial on neuroprotection with remote ischemic per-conditioning during acute ischemic stroke: the REmote iSchemic Conditioning in acUtE …
F Pico, C Rosso, E Meseguer, ML Chadenat… - 2016 - journals.sagepub.com
Rationale Remote ischemic per-conditioning—causing transient limb ischemia to induce
ischemic tolerance in other organs—reduces final infarct size in animal stroke models. Aim …
ischemic tolerance in other organs—reduces final infarct size in animal stroke models. Aim …
Limb remote-preconditioning protects against focal ischemia in rats and contradicts the dogma of therapeutic time windows for preconditioning
C Ren, X Gao, GK Steinberg, H Zhao - Neuroscience, 2008 - Elsevier
Remote ischemic preconditioning is an emerging concept for stroke treatment, but its
protection against focal stroke has not been established. We tested whether remote …
protection against focal stroke has not been established. We tested whether remote …
Remote ischemic conditioning for acute ischemic stroke: dawn in the darkness
J Pan, X Li, Y Peng - Reviews in the Neurosciences, 2016 - degruyter.com
Stroke is a leading cause of disability with high morbidity and mortality worldwide. Of all
strokes, 87% are ischemic. The only approved treatments for acute ischemic stroke are …
strokes, 87% are ischemic. The only approved treatments for acute ischemic stroke are …
Remote ischemic perconditioning is effective alone and in combination with intravenous tissue-type plasminogen activator in murine model of embolic stroke
Background and Purpose—Remote ischemic conditioning is cardioprotective in myocardial
infarction and neuroprotective in mechanical occlusion models of stroke. However, there is …
infarction and neuroprotective in mechanical occlusion models of stroke. However, there is …
Neurogenic pathway mediated remote preconditioning protects the brain from transient focal ischemic injury
S Malhotra, I Naggar, M Stewart, DM Rosenbaum - Brain research, 2011 - Elsevier
Attenuation of ischemic injury can be achieved by priming the brain with a sub-lethal
ischemic insult, a phenomenon known as ischemic preconditioning (IP). We sought to …
ischemic insult, a phenomenon known as ischemic preconditioning (IP). We sought to …
Limb remote ischemic postconditioning protects against focal ischemia in rats
Remote ischemic postconditioning (RIP) refers to an ischemia conducted in a distant organ
that protects against a prior ischemia in another organ. We tested whether RIP protects …
that protects against a prior ischemia in another organ. We tested whether RIP protects …
Remote ischemic perconditioning in thrombolysed stroke patients: randomized study of activating endogenous neuroprotection–design and MRI measurements
KD Hougaard, N Hjort, D Zeidler… - … Journal of Stroke, 2013 - journals.sagepub.com
Background Intravenous administration of alteplase is the only approved treatment for acute
ischemic stroke. Despite the effectiveness of this treatment, 50% of patients suffer chronic …
ischemic stroke. Despite the effectiveness of this treatment, 50% of patients suffer chronic …
Remote ischemic post-conditioning reduced brain damage in experimental ischemia/reperfusion injury
C Ren, M Gao, D Dornbos, Y Ding, X Zeng… - Neurological …, 2011 - Taylor & Francis
Objectives: To determine the protective effects of remote post-conditioning on ischemic brain
lesions caused by middle cerebral artery (MCA) occlusion in rats. Methods: A total of 54 …
lesions caused by middle cerebral artery (MCA) occlusion in rats. Methods: A total of 54 …
Limb remote ischemic per-conditioning in combination with post-conditioning reduces brain damage and promotes neuroglobin expression in the rat brain after …
C Ren, P Wang, B Wang, N Li, W Li… - Restorative …, 2015 - content.iospress.com
Purpose: Limb remote ischemic per-conditioning or post-conditioning has been shown to be
neuroprotective after cerebral ischemic stroke. However, the effect of combining remote per …
neuroprotective after cerebral ischemic stroke. However, the effect of combining remote per …