People with advanced cancer are at heightened risk of desire for hastened death (DHD),
suicidal ideation (SI), and completed suicide. Loss of Meaning (LoM), a component of …

Background: Clinically significant anxiety and depression are common in patients with
cancer, and are associated with poor psychiatric and medical outcomes. Historical and …

Cancer patients often develop chronic, clinically significant symptoms of depression and
anxiety. Previous studies suggest that psilocybin may decrease depression and anxiety in …

Background: A recently published randomized controlled trial compared single-dose
psilocybin with single-dose niacin in conjunction with psychotherapy in participants with …

A growing body of evidence shows that existential and spiritual well-being in cancer patients
is associated with better medical outcomes, improved quality of life, and serves as a buffer …

Recent randomized controlled trials of psilocybin-assisted psychotherapy for patients with
cancer suggest that this treatment results in large-magnitude reductions in anxiety and …

Importance Major depressive disorder (MDD) is a substantial public health burden, but
current treatments have limited effectiveness and adherence. Recent evidence suggests that …

Objective: To explore the safety and efficacy of psilocybin in patients with advanced-stage
cancer and reactive anxiety. Design: A double-blind, placebo-controlled study of patients …

Psilocybin-containing mushrooms have been consumed by various cultures in many
different parts of the world for thousands of years. Psilocybin, a classic psychedelic, contains …

Cancer is highly prevalent and one of the leading causes of global morbidity and mortality.
Psychological and existential suffering is common in cancer patients, associated with poor …