Improved strategies for the treatment of tendon defects are required to successfully restore
mechanical function and strength to the damaged tissue. This remains a scientific and …

Tendon injuries continuously rise, and regeneration is not only slow, but also limited due to
the poor endogenous healing ability of the tendon tissue. Tissue grafts constitute the clinical …

Structural and hierarchical anisotropy underlies the structure-function relationship of most
living tissues. Attempts to exploit the interplay between cells and their immediate …

Poor tendon repair remains a clinical problem due to the difficulties in replicating the
complex multiscale hierarchical structure of native tendons. In this work, a bioinspired …

A braided multiscale fibrous scaffold consisting of aligned PCL micro/collagen-bFGFnano
fibers was fabricated (mPCL-nCol-bFGF) to mimic native tendon tissue architecture which …

The long-term success of surgical repair of rotator cuff tears is largely dependent on
restoration of a functional tendon-to-bone interface. We implemented micro-precise …

Approximately 800, 000 surgical repairs are performed annually in the US for debilitating
injuries to ligaments and tendons of the foot, ankle, knee, wrist, elbow and shoulder …

Tendon tissue connects muscle to bone and plays crucial roles in stress transfer. Tendon
injury remains a significant clinical challenge due to its complicated biological structure and …

Tendon injuries are the leading cause of chronic debilitation to patients. Tendon
stem/progenitor cells (TSPCs) are potential seed cells for tendon tissue engineering and …

Lesions of tendons and ligaments account for over 40% of the musculoskeletal lesions.
Surgical techniques and materials for repair and regeneration are currently not satisfactory …