Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
A Taddei, C Giampietro, A Conti, F Orsenigo… - Nature cell …, 2008 - nature.com
Intercellular junctions mediate adhesion and communication between adjoining cells.
Although formed by different molecules, tight junctions (TJs) and adherens junctions (AJs) …
Although formed by different molecules, tight junctions (TJs) and adherens junctions (AJs) …
VE-cadherin and claudin-5: it takes two to tango
J Gavard, JS Gutkind - Nature cell biology, 2008 - nature.com
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5,
which are key components of adherens and tight endothelial junctions, respectively …
which are key components of adherens and tight endothelial junctions, respectively …
[HTML][HTML] Adherens and tight junctions: structure, function and connections to the actin cytoskeleton
A Hartsock, WJ Nelson - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Adherens junctions and Tight junctions comprise two modes of cell–cell adhesion that
provide different functions. Both junctional complexes are proposed to associate with the …
provide different functions. Both junctional complexes are proposed to associate with the …
ZO-1 recruitment to α-catenin–a novel mechanism for coupling the assembly of tight junctions to adherens junctions
JL Maiers, X Peng, AS Fanning… - Journal of cell …, 2013 - journals.biologists.com
The formation of a barrier between epithelial cells is a fundamental determinant of cellular
homeostasis, protecting underlying cells against pathogens, dehydration and damage …
homeostasis, protecting underlying cells against pathogens, dehydration and damage …
Tight junctions at a glance
MS Balda, K Matter - Journal of cell science, 2008 - journals.biologists.com
Tight junctions (TJs) are morphologically distinct and highly regulated areas of close contact
between the plasma membranes of neighbouring epithelial and endothelial cells. They are …
between the plasma membranes of neighbouring epithelial and endothelial cells. They are …
The structure and regulation of tight junctions
JM Anderson, MS Balda, AS Fanning - Current opinion in cell biology, 1993 - Elsevier
Tight junctions create a paracellular barrier between both epithelial and endothelial cells.
Recent advances have helped define their molecular composition and regulation. Studies in …
Recent advances have helped define their molecular composition and regulation. Studies in …
A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells
Tight junctions (TJs) seal the intercellular space of epithelial cells, while individual epithelial
cells move against adjacent cells in cellular sheets. To observe TJs in live epithelial cellular …
cells move against adjacent cells in cellular sheets. To observe TJs in live epithelial cellular …
Cell adhesion at the tight junctions: new aspects and new functions
N Wibbe, K Ebnet - Cells, 2023 - mdpi.com
Tight junctions (TJ) are cell–cell adhesive structures that define the permeability of barrier-
forming epithelia and endothelia. In contrast to this seemingly static function, TJs display a …
forming epithelia and endothelia. In contrast to this seemingly static function, TJs display a …
Distinct subdomain organization and molecular composition of a tight junction with adherens junction features
Most polarized epithelia constrain solute diffusion between luminal and interstitial
compartments using tight junctions and generate mechanical strength using adherens …
compartments using tight junctions and generate mechanical strength using adherens …
α-Catenin as a tension transducer that induces adherens junction development
S Yonemura, Y Wada, T Watanabe, A Nagafuchi… - Nature cell …, 2010 - nature.com
Adherens junctions (AJs), which are organized by adhesion proteins and the underlying
actin cytoskeleton, probably sense pulling forces from adjacent cells and modulate opposing …
actin cytoskeleton, probably sense pulling forces from adjacent cells and modulate opposing …