Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5

A Taddei, C Giampietro, A Conti, F Orsenigo… - Nature cell …, 2008 - nature.com
Intercellular junctions mediate adhesion and communication between adjoining cells.
Although formed by different molecules, tight junctions (TJs) and adherens junctions (AJs) …

VE-cadherin and claudin-5: it takes two to tango

J Gavard, JS Gutkind - Nature cell biology, 2008 - nature.com
Endothelial barrier function requires the adhesive activity of VE-cadherin and claudin-5,
which are key components of adherens and tight endothelial junctions, respectively …

[HTML][HTML] Adherens and tight junctions: structure, function and connections to the actin cytoskeleton

A Hartsock, WJ Nelson - Biochimica et Biophysica Acta (BBA) …, 2008 - Elsevier
Adherens junctions and Tight junctions comprise two modes of cell–cell adhesion that
provide different functions. Both junctional complexes are proposed to associate with the …

ZO-1 recruitment to α-catenin–a novel mechanism for coupling the assembly of tight junctions to adherens junctions

JL Maiers, X Peng, AS Fanning… - Journal of cell …, 2013 - journals.biologists.com
The formation of a barrier between epithelial cells is a fundamental determinant of cellular
homeostasis, protecting underlying cells against pathogens, dehydration and damage …

Tight junctions at a glance

MS Balda, K Matter - Journal of cell science, 2008 - journals.biologists.com
Tight junctions (TJs) are morphologically distinct and highly regulated areas of close contact
between the plasma membranes of neighbouring epithelial and endothelial cells. They are …

The structure and regulation of tight junctions

JM Anderson, MS Balda, AS Fanning - Current opinion in cell biology, 1993 - Elsevier
Tight junctions create a paracellular barrier between both epithelial and endothelial cells.
Recent advances have helped define their molecular composition and regulation. Studies in …

A peculiar internalization of claudins, tight junction-specific adhesion molecules, during the intercellular movement of epithelial cells

M Matsuda, A Kubo, M Furuse… - Journal of cell …, 2004 - journals.biologists.com
Tight junctions (TJs) seal the intercellular space of epithelial cells, while individual epithelial
cells move against adjacent cells in cellular sheets. To observe TJs in live epithelial cellular …

Cell adhesion at the tight junctions: new aspects and new functions

N Wibbe, K Ebnet - Cells, 2023 - mdpi.com
Tight junctions (TJ) are cell–cell adhesive structures that define the permeability of barrier-
forming epithelia and endothelia. In contrast to this seemingly static function, TJs display a …

Distinct subdomain organization and molecular composition of a tight junction with adherens junction features

FD Nunes, LN Lopez, HW Lin, C Davies… - Journal of cell …, 2006 - journals.biologists.com
Most polarized epithelia constrain solute diffusion between luminal and interstitial
compartments using tight junctions and generate mechanical strength using adherens …

α-Catenin as a tension transducer that induces adherens junction development

S Yonemura, Y Wada, T Watanabe, A Nagafuchi… - Nature cell …, 2010 - nature.com
Adherens junctions (AJs), which are organized by adhesion proteins and the underlying
actin cytoskeleton, probably sense pulling forces from adjacent cells and modulate opposing …