[HTML][HTML] Genome editing: an essential technology for cancer treatment

M Tufail - Medicine in Omics, 2022 - Elsevier
When genetic engineering was first developed in the 1970s, it opened new possibilities for
genome editing. The life sciences have reaped numerous gains from gene-editing …

CRISPR/Cas9–An evolving biological tool kit for cancer biology and oncology

X Tian, T Gu, S Patel, AM Bode, MH Lee… - NPJ precision …, 2019 - nature.com
The development of genetic engineering in the 1970s marked a new frontier in genome-
editing technology. Gene-editing technologies have provided a plethora of benefits to the life …

CRISPR/Cas9-Mediated Genome Editing in Cancer Therapy

S Ding, J Liu, X Han, M Tang - International Journal of Molecular Sciences, 2023 - mdpi.com
The Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated
protein 9 (CRISPR/Cas9) system, an RNA-based adaptive immune system found in bacteria …

CRISPR-Cas9: A potent gene-editing tool for the treatment of cancer

G Mishra, K Srivastava, J Rais, M Dixit… - Current Molecular …, 2024 - ingentaconnect.com
The prokaryotic adaptive immune system has clustered regularly interspaced short
palindromic repeat. CRISPR-associated protein (CRISPR-Cas) genome editing systems …

Application of CRISPR/Cas9 gene editing technique in the study of cancer treatment

C Jiang, L Meng, B Yang, X Luo - Clinical genetics, 2020 - Wiley Online Library
In recent years, gene editing, especially that using clustered regularly interspaced short
palindromic repeat (CRISPR)/Cas9, has made great progress in the field of gene function …

Genome-editing approaches and applications: a brief review on CRISPR technology and its role in cancer

N Siva, S Gupta, A Gupta, JN Shukla, B Malik, N Shukla - 3 Biotech, 2021 - Springer
The development of genome-editing technologies in 1970s has discerned a new beginning
in the field of science. Out of different genome-editing approaches such as Zing-finger …

Genome editing approaches with CRISPR/Cas9 for cancer treatment: Critical appraisal of preclinical and clinical utility, challenges, and future research

S Chira, A Nutu, E Isacescu, C Bica, L Pop, C Ciocan… - Cells, 2022 - mdpi.com
The increasing burden on human malignant diseases became a major concern for
healthcare practitioners, that must deal with tumor relapse and the inability to efficiently treat …

Exploring the CRISPR/Cas9 system in targeting drug resistant cancer stem cells

R Gulati, MN Ramavath, VSMK Metta… - Annals of the …, 2021 - annalsofrscb.ro
The genome-editing technology CRISPR/Cas9 holds great promise for the discovery of
therapeutic targets in cancer and other diseases. With the help of this system, DNA can be …

Targeting cancer with CRISPR/Cas9-based therapy

K Balon, A Sheriff, J Jacków, Ł Łaczmański - International journal of …, 2022 - mdpi.com
Cancer is a devastating condition characterised by the uncontrolled division of cells with
many forms remaining resistant to current treatment. A hallmark of cancer is the gradual …

Review of applications of CRISPR-Cas9 gene-editing technology in cancer research

Z Zhao, C Li, F Tong, J Deng, G Huang… - Biological procedures …, 2021 - Springer
Characterized by multiple complex mutations, including activation by oncogenes and
inhibition by tumor suppressors, cancer is one of the leading causes of death. Application of …